MRPL42 (mitochondrial ribosomal protein L42)

2019-04-01  

Identity

HGNC
LOCATION
12q22
LOCUSID
ALIAS
HSPC204,L31MT,L42MT,MRP-L31,MRP-L42,MRP-S32,MRPL31,MRPS32,PTD007,RPML31,S32MT
FUSION GENES

Other Information

Locus ID:

NCBI: 28977
MIM: 611847
HGNC: 14493
Ensembl: ENSG00000198015

Variants:

dbSNP: 28977
ClinVar: 28977
TCGA: ENSG00000198015
COSMIC: MRPL42

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198015ENST00000358678J3KP21
ENSG00000198015ENST00000393128J3KPP0
ENSG00000198015ENST00000547098S4R2Z7
ENSG00000198015ENST00000548545S4R360
ENSG00000198015ENST00000549561Q9Y6G3
ENSG00000198015ENST00000549561A0A024RBG3
ENSG00000198015ENST00000549982Q9Y6G3
ENSG00000198015ENST00000549982A0A024RBG3
ENSG00000198015ENST00000551396F8VVR0
ENSG00000198015ENST00000552217Q9Y6G3
ENSG00000198015ENST00000552217A0A024RBG3

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
295310152018Knockdown of MRPL42 suppresses glioma cell proliferation by inducing cell cycle arrest and apoptosis.8
295310152018Knockdown of MRPL42 suppresses glioma cell proliferation by inducing cell cycle arrest and apoptosis.8
261079022015[Comparative analysis of the role of CD4(+) and CD8(+) T cells in severe asthma development].1
261079022015[Comparative analysis of the role of CD4(+) and CD8(+) T cells in severe asthma development].1
205466122010The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.28
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
205466122010The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.28
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20

Citation

Dessen P

MRPL42 (mitochondrial ribosomal protein L42)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57951/mrpl42-(mitochondrial-ribosomal-protein-l42)