JPT2 (Jupiter microtubule associated homolog 2)

2019-04-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
C16orf34,HN1L,L11

Other Information

Locus ID:

NCBI: 90861
HGNC: 14137
Ensembl: ENSG00000206053

Variants:

dbSNP: 90861
ClinVar: 90861
TCGA: ENSG00000206053
COSMIC: JPT2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000206053ENST00000248098Q9H910
ENSG00000206053ENST00000382710A6NGP5
ENSG00000206053ENST00000382711Q9H910
ENSG00000206053ENST00000561516H3BMM8
ENSG00000206053ENST00000562569H3BTV5
ENSG00000206053ENST00000562684Q9H910
ENSG00000206053ENST00000565851H3BU16
ENSG00000206053ENST00000566691H3BMT0
ENSG00000206053ENST00000566742H3BMV3
ENSG00000206053ENST00000566925H3BS08
ENSG00000206053ENST00000569765B4E1P3

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
384171232024JPT2 Affects Trophoblast Functions and Macrophage Polarization and Metabolism, and Acts as a Potential Therapeutic Target for Recurrent Spontaneous Abortion.1
384171232024JPT2 Affects Trophoblast Functions and Macrophage Polarization and Metabolism, and Acts as a Potential Therapeutic Target for Recurrent Spontaneous Abortion.1
376072182023Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12.2
376072182023Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12.2
345191272022HN1L promotes stem cell-like properties by regulating TGF-β signaling pathway through targeting FOXP2 in prostate cancer.5
364769882022HN1L/AP-2γ/PLK1 signaling drives tumor progression and chemotherapy resistance in esophageal squamous cell carcinoma.4
345191272022HN1L promotes stem cell-like properties by regulating TGF-β signaling pathway through targeting FOXP2 in prostate cancer.5
364769882022HN1L/AP-2γ/PLK1 signaling drives tumor progression and chemotherapy resistance in esophageal squamous cell carcinoma.4
331916172021HN1L promotes migration and invasion of breast cancer by up-regulating the expression of HMGB1.10
334714192021HN1L promotes invasion and metastasis of the esophagogastric junction adenocarcinoma.7
337580612021Essential requirement for JPT2 in NAADP-evoked Ca(2+) signaling.40
337580622021HN1L/JPT2: A signaling protein that connects NAADP generation to Ca(2+) microdomain formation.32
331916172021HN1L promotes migration and invasion of breast cancer by up-regulating the expression of HMGB1.10
334714192021HN1L promotes invasion and metastasis of the esophagogastric junction adenocarcinoma.7
337580612021Essential requirement for JPT2 in NAADP-evoked Ca(2+) signaling.40

Citation

Dessen P

JPT2 (Jupiter microtubule associated homolog 2)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57967/jpt2-(jupiter-microtubule-associated-homolog-2)