Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51571
MIM: 617978
HGNC: 25216
Ensembl: ENSG00000153310
Variants:
dbSNP: 51571
ClinVar: 51571
TCGA: ENSG00000153310
COSMIC: CYRIB
RNA/Proteins
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37540188 | 2024 | LANCL1, a cell surface protein, promotes liver tumor initiation through FAM49B-Rac1 axis to suppress oxidative stress. | 0 |
| 38712822 | 2024 | CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake. | 1 |
| 37540188 | 2024 | LANCL1, a cell surface protein, promotes liver tumor initiation through FAM49B-Rac1 axis to suppress oxidative stress. | 0 |
| 38712822 | 2024 | CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake. | 1 |
| 37264948 | 2023 | A genome-wide genetic screen identifies CYRI-B as a negative regulator of CEACAM3-mediated phagocytosis. | 0 |
| 37264948 | 2023 | A genome-wide genetic screen identifies CYRI-B as a negative regulator of CEACAM3-mediated phagocytosis. | 0 |
| 36499755 | 2022 | GOLM1 and FAM49B: Potential Biomarkers in HNSCC Based on Bioinformatics and Immunohistochemical Analysis. | 3 |
| 36499755 | 2022 | GOLM1 and FAM49B: Potential Biomarkers in HNSCC Based on Bioinformatics and Immunohistochemical Analysis. | 3 |
| 33217330 | 2021 | Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1. | 7 |
| 33217330 | 2021 | Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1. | 7 |
| 32071545 | 2020 | TASP1 Promotes Gallbladder Cancer Cell Proliferation and Metastasis by Up-regulating FAM49B via PI3K/AKT Pathway. | 19 |
| 32071545 | 2020 | TASP1 Promotes Gallbladder Cancer Cell Proliferation and Metastasis by Up-regulating FAM49B via PI3K/AKT Pathway. | 19 |
| 31285585 | 2019 | CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection. | 23 |
| 31285585 | 2019 | CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection. | 23 |
| 29059164 | 2018 | FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis. | 35 |
Citation
Dessen P
CYRIB (CYFIP related Rac1 interactor B)
Atlas Genet Cytogenet Oncol Haematol. 2019-04-01
Online version: http://atlasgeneticsoncology.org/gene/57975/cyrib-(cyfip-related-rac1-interactor-b)
