ZNHIT1 (zinc finger HIT-type containing 1)

2019-05-01  

Identity

HGNC
ZNHIT1
LOCATION
7q22.1
LOCUSID
10467
ALIAS
CG1I,ZNFN4A1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10467
MIM: 618617
HGNC: 21688
Ensembl: ENSG00000106400

Variants:

dbSNP: 10467
ClinVar: 10467
TCGA: ENSG00000106400
COSMIC: ZNHIT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106400ENST00000305105O43257

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
371787412023A combined proteomics and bioinformatics analysis of ZNHIT1-interacting proteins reveals a significant enrichment in proteins associated with mitochondrial function.0
371787412023A combined proteomics and bioinformatics analysis of ZNHIT1-interacting proteins reveals a significant enrichment in proteins associated with mitochondrial function.0
351755582022Gene Co-expression Analysis of the Human Substantia Nigra Identifies ZNHIT1 as an SNCA Co-expressed Gene that Protects Against α-Synuclein-Induced Impairments in Neurite Growth and Mitochondrial Dysfunction in SH-SY5Y Cells.1
359780752022Znhit1 and HIF-2α are correlated with cancer stem cell markers in breast cancer patients.2
351755582022Gene Co-expression Analysis of the Human Substantia Nigra Identifies ZNHIT1 as an SNCA Co-expressed Gene that Protects Against α-Synuclein-Induced Impairments in Neurite Growth and Mitochondrial Dysfunction in SH-SY5Y Cells.1
359780752022Znhit1 and HIF-2α are correlated with cancer stem cell markers in breast cancer patients.2
173801232007A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis.41
177000682007p18(Hamlet) mediates different p53-dependent responses to DNA-damage inducing agents.15
173801232007A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis.41
177000682007p18(Hamlet) mediates different p53-dependent responses to DNA-damage inducing agents.15

Citation

Dessen P

ZNHIT1 (zinc finger HIT-type containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2019-05-01

Online version: http://atlasgeneticsoncology.org/gene/58002/znhit1-(zinc-finger-hit-type-containing-1)