Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23001
MIM: 617485
HGNC: 20751
Ensembl: ENSG00000163625
Variants:
dbSNP: 23001
ClinVar: 23001
TCGA: ENSG00000163625
COSMIC: WDFY3
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35099014 | 2022 | ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration. | 0 |
| 36566259 | 2022 | A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis. | 5 |
| 35099014 | 2022 | ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration. | 0 |
| 36566259 | 2022 | A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis. | 5 |
| 33225481 | 2021 | A highly conserved glutamic acid in ALFY inhibits membrane binding to aid in aggregate clearance. | 4 |
| 33225481 | 2021 | A highly conserved glutamic acid in ALFY inhibits membrane binding to aid in aggregate clearance. | 4 |
| 31899071 | 2020 | Huntington's Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy. | 31 |
| 31899071 | 2020 | Huntington's Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy. | 31 |
| 31327001 | 2019 | Pathogenic WDFY3 variants cause neurodevelopmental disorders and opposing effects on brain size. | 22 |
| 31327001 | 2019 | Pathogenic WDFY3 variants cause neurodevelopmental disorders and opposing effects on brain size. | 22 |
| 29021535 | 2017 | The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells. | 10 |
| 29021535 | 2017 | The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells. | 10 |
| 27008544 | 2016 | ALFY-Controlled DVL3 Autophagy Regulates Wnt Signaling, Determining Human Brain Size. | 45 |
| 27648578 | 2016 | Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain. | 53 |
| 27008544 | 2016 | ALFY-Controlled DVL3 Autophagy Regulates Wnt Signaling, Determining Human Brain Size. | 45 |
Citation
Dessen P
WDFY3 (WD repeat and FYVE domain containing 3)
Atlas Genet Cytogenet Oncol Haematol. 2019-08-01
Online version: http://atlasgeneticsoncology.org/gene/58031/haematological-explorer/meetings/
