LYPD8 (LY6/PLAUR domain containing 8)

2019-08-01 Affiliation

Identity

HGNC

LYPD8

LOCATION

1q44

LOCUSID

646627

ALIAS

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 646627
MIM: 617067
HGNC: 44208
Ensembl: ENSG00000259823

Variants:

dbSNP: 646627
ClinVar: 646627
TCGA: ENSG00000259823
COSMIC: LYPD8

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000259823	ENST00000590317	Q6UX82

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Metabolism of proteins	REACTOME	R-HSA-392499
Post-translational protein modification	REACTOME	R-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteins	REACTOME	R-HSA-163125

References

Pubmed ID	Year	Title	Citations
33822948	2021	Alleviation of colonic inflammation by Lypd8 in a mouse model of inflammatory bowel disease.	5
33822948	2021	Alleviation of colonic inflammation by Lypd8 in a mouse model of inflammatory bowel disease.	5
30816524	2019	LYPD8 regulates the proliferation and migration of colorectal cancer cells through inhibiting the secretion of IL‑6 and TNF‑α.	3
30816524	2019	LYPD8 regulates the proliferation and migration of colorectal cancer cells through inhibiting the secretion of IL‑6 and TNF‑α.	3

Citation

Dessen P

LYPD8 (LY6/PLAUR domain containing 8)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58072/lypd8-(ly6-plaur-domain-containing-8)