Identity
HGNC
LOCATION
16p11.2
LOCUSID
ALIAS
HSpin1,LAT,PP2030,SLC62A1,SLC63A1,SPIN1,SPINL,nrs
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 83985
MIM: 612583
HGNC: 30621
Ensembl: ENSG00000169682
Variants:
dbSNP: 83985
ClinVar: 83985
TCGA: ENSG00000169682
COSMIC: SPNS1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36161949 | 2022 | Spns1 is a lysophospholipid transporter mediating lysosomal phospholipid salvage. | 20 |
| 36161949 | 2022 | Spns1 is a lysophospholipid transporter mediating lysosomal phospholipid salvage. | 20 |
| 29547122 | 2018 | SPIN1 promotes tumorigenesis by blocking the uL18 (universal large ribosomal subunit protein 18)-MDM2-p53 pathway in human cancer. | 27 |
| 29547122 | 2018 | SPIN1 promotes tumorigenesis by blocking the uL18 (universal large ribosomal subunit protein 18)-MDM2-p53 pathway in human cancer. | 27 |
| 29162837 | 2017 | L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human Niemann-Pick type C disease. | 13 |
| 29162837 | 2017 | L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human Niemann-Pick type C disease. | 13 |
| 22942098 | 2012 | Polymorphisms in sh2b1 and spns1 loci are associated with triglyceride levels in a healthy population in northern Sweden. | 4 |
| 22942098 | 2012 | Polymorphisms in sh2b1 and spns1 loci are associated with triglyceride levels in a healthy population in northern Sweden. | 4 |
| 11340170 | 2001 | Mutations in the novel membrane protein spinster interfere with programmed cell death and cause neural degeneration in Drosophila melanogaster. | 50 |
| 11340170 | 2001 | Mutations in the novel membrane protein spinster interfere with programmed cell death and cause neural degeneration in Drosophila melanogaster. | 50 |
Citation
Dessen P
SPNS1 (sphingolipid transporter 1 (putative))
Atlas Genet Cytogenet Oncol Haematol. 2019-08-01
Online version: http://atlasgeneticsoncology.org/gene/58075/spns1-(sphingolipid-transporter-1-(putative))
