Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 494551
MIM: 614084
HGNC: 19684
Ensembl: ENSG00000214102
Variants:
dbSNP: 494551
ClinVar: 494551
TCGA: ENSG00000214102
COSMIC: WEE2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000214102 | ENST00000397541 | P0C1S8 |
| ENSG00000214102 | ENST00000493845 | H7C5P0 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cell cycle | KEGG | ko04110 |
| Cell cycle | KEGG | hsa04110 |
| Cell cycle - G2/M transition | KEGG | hsa_M00693 |
| Cell cycle - G2/M transition | KEGG | M00693 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37772619 | 2023 | Novel WEE2 homozygous mutations c.1346C>T and c.949A>T identified in primary infertile women due to unexplained fertilization failure. | 1 |
| 37772619 | 2023 | Novel WEE2 homozygous mutations c.1346C>T and c.949A>T identified in primary infertile women due to unexplained fertilization failure. | 1 |
| 33904356 | 2021 | Clinical exome sequencing identifies novel compound heterozygous mutations of the WEE2 gene in primary infertile women with fertilization failure. | 4 |
| 34476630 | 2021 | Novel WEE2 compound heterozygous mutations identified in patients with fertilization failure or poor fertilization. | 5 |
| 33904356 | 2021 | Clinical exome sequencing identifies novel compound heterozygous mutations of the WEE2 gene in primary infertile women with fertilization failure. | 4 |
| 34476630 | 2021 | Novel WEE2 compound heterozygous mutations identified in patients with fertilization failure or poor fertilization. | 5 |
| 30471857 | 2019 | Hepatitis B virus X protein related lncRNA WEE2-AS1 promotes hepatocellular carcinoma proliferation and invasion. | 17 |
| 30628060 | 2019 | Novel mutations in WEE2: Expanding the spectrum of mutations responsible for human fertilization failure. | 15 |
| 30827523 | 2019 | New biallelic mutations in WEE2: expanding the spectrum of mutations that cause fertilization failure or poor fertilization. | 18 |
| 30827524 | 2019 | Novel WEE2 gene variants identified in patients with fertilization failure and female infertility. | 14 |
| 31428887 | 2019 | Novel compound heterozygous mutations in WEE2 causes female infertility and fertilization failure. | 14 |
| 30471857 | 2019 | Hepatitis B virus X protein related lncRNA WEE2-AS1 promotes hepatocellular carcinoma proliferation and invasion. | 17 |
| 30628060 | 2019 | Novel mutations in WEE2: Expanding the spectrum of mutations responsible for human fertilization failure. | 15 |
| 30827523 | 2019 | New biallelic mutations in WEE2: expanding the spectrum of mutations that cause fertilization failure or poor fertilization. | 18 |
| 30827524 | 2019 | Novel WEE2 gene variants identified in patients with fertilization failure and female infertility. | 14 |
Citation
Dessen P
WEE2 (WEE2 oocyte meiosis inhibiting kinase)
Atlas Genet Cytogenet Oncol Haematol. 2019-08-01
Online version: http://atlasgeneticsoncology.org/gene/58088/wee2-(wee2-oocyte-meiosis-inhibiting-kinase)
