PMP2 (peripheral myelin protein 2)

2019-08-01  

Identity

HGNC
LOCATION
8q21.13
LOCUSID
ALIAS
CMT1G,FABP8,M-FABP,MP2,P2

Other Information

Locus ID:

NCBI: 5375
MIM: 170715
HGNC: 9117
Ensembl: ENSG00000147588

Variants:

dbSNP: 5375
ClinVar: 5375
TCGA: ENSG00000147588
COSMIC: PMP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147588ENST00000256103P02689
ENSG00000147588ENST00000519260E5RH45

Expression (GTEx)

0
100
200
300
400
500
600

References

Pubmed IDYearTitleCitations
341385182021Human myelin protein P2: from crystallography to time-lapse membrane imaging and neuropathy-associated variants.6
347582972021PMP2/FABP8 induces PI(4,5)P(2)-dependent transbilayer reorganization of sphingomyelin in the plasma membrane.11
341385182021Human myelin protein P2: from crystallography to time-lapse membrane imaging and neuropathy-associated variants.6
347582972021PMP2/FABP8 induces PI(4,5)P(2)-dependent transbilayer reorganization of sphingomyelin in the plasma membrane.11
322652982020Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.5
322775372020Early onset demyelinating Charcot-Marie-Tooth disease caused by a novel in-frame isoleucine deletion in peripheral myelin protein 2.3
322652982020Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.5
322775372020Early onset demyelinating Charcot-Marie-Tooth disease caused by a novel in-frame isoleucine deletion in peripheral myelin protein 2.3
305068952019The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion.14
314129002019Peripheral myelin protein 2 - a novel cluster of mutations causing Charcot-Marie-Tooth neuropathy.3
305068952019The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion.14
314129002019Peripheral myelin protein 2 - a novel cluster of mutations causing Charcot-Marie-Tooth neuropathy.3
293363622018Screening for SH3TC2, PMP2, and BSCL2 Variants in a Cohort of Chinese Patients with Charcot-Marie-Tooth.2
299409442018Structure and dynamics of a human myelin protein P2 portal region mutant indicate opening of the β barrel in fatty acid binding proteins.10
293363622018Screening for SH3TC2, PMP2, and BSCL2 Variants in a Cohort of Chinese Patients with Charcot-Marie-Tooth.2

Citation

Dessen P

PMP2 (peripheral myelin protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58097/pmp2-(peripheral-myelin-protein-2)