MARCHF8 (membrane associated ring-CH-type finger 8)

2019-08-01  

Identity

HGNC
LOCATION
10q11.21
LOCUSID
ALIAS
CMIR,MARCH-VIII,MARCH8,MIR,RNF178,c-MIR

Other Information

Locus ID:

NCBI: 220972
MIM: 613335
HGNC: 23356
Ensembl: ENSG00000165406

Variants:

dbSNP: 220972
ClinVar: 220972
TCGA: ENSG00000165406
COSMIC: MARCHF8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165406ENST00000319836Q5T0T0
ENSG00000165406ENST00000319836A0A024R7U2
ENSG00000165406ENST00000395769Q5T0T0
ENSG00000165406ENST00000395769A0A024R7U2
ENSG00000165406ENST00000453424Q5T0T0
ENSG00000165406ENST00000453980A0A0A0MSM7

References

Pubmed IDYearTitleCitations
382268142024The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer.2
382997432024Human MARCH1, 2, and 8 block Ebola virus envelope glycoprotein cleavage via targeting furin P domain.2
382268142024The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer.2
382997432024Human MARCH1, 2, and 8 block Ebola virus envelope glycoprotein cleavage via targeting furin P domain.2
368676602023HPV upregulates MARCHF8 ubiquitin ligase and inhibits apoptosis by degrading the death receptors in head and neck cancer.7
370988352023Ubiquitin ligase MARCH8 promotes the malignant progression of hepatocellular carcinoma through PTEN ubiquitination and degradation.2
377479372023E3 Ubiquitin Ligase MARCH8 Promotes Pancreatic Cancer Growth and Metastasis by Activating STAT3 via Degradation of PTPN4.1
377728222023EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8.0
368676602023HPV upregulates MARCHF8 ubiquitin ligase and inhibits apoptosis by degrading the death receptors in head and neck cancer.7
370988352023Ubiquitin ligase MARCH8 promotes the malignant progression of hepatocellular carcinoma through PTEN ubiquitination and degradation.2
377479372023E3 Ubiquitin Ligase MARCH8 Promotes Pancreatic Cancer Growth and Metastasis by Activating STAT3 via Degradation of PTPN4.1
377728222023EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8.0
360647062022Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer.3
360647062022Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer.3
341834492021Membrane-Associated RING-CH 8 Functions as a Novel PD-L1 E3 Ligase to Mediate PD-L1 Degradation Induced by EGFR Inhibitors.18

Citation

Dessen P

MARCHF8 (membrane associated ring-CH-type finger 8)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58101/marchf8-(membrane-associated-ring-ch-type-finger-8)