Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 717
MIM: 613927
HGNC: 1248
Ensembl: ENSG00000166278
Variants:
dbSNP: 717
ClinVar: 717
TCGA: ENSG00000166278
COSMIC: C2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36194249 | 2023 | Proteomic analysis of diabetes genetic risk scores identifies complement C2 and neuropilin-2 as predictors of type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) Study. | 2 |
| 36194249 | 2023 | Proteomic analysis of diabetes genetic risk scores identifies complement C2 and neuropilin-2 as predictors of type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) Study. | 2 |
| 34899688 | 2021 | Gain-of-Function Mutations R249C and S250C in Complement C2 Protein Increase C3 Deposition in the Presence of C-Reactive Protein. | 7 |
| 34899688 | 2021 | Gain-of-Function Mutations R249C and S250C in Complement C2 Protein Increase C3 Deposition in the Presence of C-Reactive Protein. | 7 |
| 32164349 | 2020 | Hereditary Deficiency of the Second Component of Complement: Early Diagnosis and 21-Year Follow-Up of a Family. | 0 |
| 32913345 | 2020 | Complement protein levels and MBL2 polymorphisms are associated with dengue and disease severity. | 7 |
| 32164349 | 2020 | Hereditary Deficiency of the Second Component of Complement: Early Diagnosis and 21-Year Follow-Up of a Family. | 0 |
| 32913345 | 2020 | Complement protein levels and MBL2 polymorphisms are associated with dengue and disease severity. | 7 |
| 29283494 | 2018 | Genetic association of complement component 2 variants with chronic hepatitis B in a Korean population. | 3 |
| 30179527 | 2018 | Association Between Complement Factor C2/C3/CFB/CFH Polymorphisms and Age-Related Macular Degeneration: A Meta-Analysis. | 20 |
| 29283494 | 2018 | Genetic association of complement component 2 variants with chronic hepatitis B in a Korean population. | 3 |
| 30179527 | 2018 | Association Between Complement Factor C2/C3/CFB/CFH Polymorphisms and Age-Related Macular Degeneration: A Meta-Analysis. | 20 |
| 28742139 | 2017 | Acquisition of C1 inhibitor by Bordetella pertussis virulence associated gene 8 results in C2 and C4 consumption away from the bacterial surface. | 22 |
| 28742139 | 2017 | Acquisition of C1 inhibitor by Bordetella pertussis virulence associated gene 8 results in C2 and C4 consumption away from the bacterial surface. | 22 |
| 27252379 | 2016 | Solution Structures of Complement C2 and Its C4 Complexes Propose Pathway-specific Mechanisms for Control and Activation of the Complement Proconvertases. | 15 |
Citation
Dessen P
C2 (complement C2)
Atlas Genet Cytogenet Oncol Haematol. 2019-08-01
Online version: http://atlasgeneticsoncology.org/gene/58120/c2-(complement-c2)
