Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8565
MIM: 603623
HGNC: 12840
Ensembl: ENSG00000134684
Variants:
dbSNP: 8565
ClinVar: 8565
TCGA: ENSG00000134684
COSMIC: YARS1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000134684 | ENST00000373477 | P54577 |
| ENSG00000134684 | ENST00000373477 | A0A0S2Z4R1 |
| ENSG00000134684 | ENST00000616261 | A0A0C4DGZ5 |
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36890170 | 2023 | Tyrosyl-tRNA synthetase has a noncanonical function in actin bundling. | 3 |
| 36890170 | 2023 | Tyrosyl-tRNA synthetase has a noncanonical function in actin bundling. | 3 |
| 34352414 | 2021 | Novel partial loss-of-function variants in the tyrosyl-tRNA synthetase 1 (YARS1) gene involved in multisystem disease. | 2 |
| 34536092 | 2021 | The recurrent missense mutation p.(Arg367Trp) in YARS1 causes a distinct neurodevelopmental phenotype. | 2 |
| 34352414 | 2021 | Novel partial loss-of-function variants in the tyrosyl-tRNA synthetase 1 (YARS1) gene involved in multisystem disease. | 2 |
| 34536092 | 2021 | The recurrent missense mutation p.(Arg367Trp) in YARS1 causes a distinct neurodevelopmental phenotype. | 2 |
| 31771979 | 2020 | Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage. | 11 |
| 31912229 | 2020 | YARS as an oncogenic protein that promotes gastric cancer progression through activating PI3K-Akt signaling. | 22 |
| 31771979 | 2020 | Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage. | 11 |
| 31912229 | 2020 | YARS as an oncogenic protein that promotes gastric cancer progression through activating PI3K-Akt signaling. | 22 |
| 30304524 | 2019 | Homozygosity for a mutation affecting the catalytic domain of tyrosyl-tRNA synthetase (YARS) causes multisystem disease. | 11 |
| 30939244 | 2019 | Resveratrol targets TyrRS acetylation to protect against radiation-induced damage. | 9 |
| 30304524 | 2019 | Homozygosity for a mutation affecting the catalytic domain of tyrosyl-tRNA synthetase (YARS) causes multisystem disease. | 11 |
| 30939244 | 2019 | Resveratrol targets TyrRS acetylation to protect against radiation-induced damage. | 9 |
| 29289698 | 2018 | Tyrosyl-tRNA synthetase: A potential kyotorphin synthetase in mammals. | 2 |
Citation
Dessen P
YARS1 (tyrosyl-tRNA synthetase 1)
Atlas Genet Cytogenet Oncol Haematol. 2019-08-01
Online version: http://atlasgeneticsoncology.org/gene/58124/meetings/case-report-explorer/
