ISG20L2 (interferon stimulated exonuclease gene 20 like 2)

2019-08-01  

Identity

HGNC
LOCATION
1q23.1
LOCUSID
ALIAS
HSD38

Other Information

Locus ID:

NCBI: 81875
MIM: 611930
HGNC: 25745
Ensembl: ENSG00000143319

Variants:

dbSNP: 81875
ClinVar: 81875
TCGA: ENSG00000143319
COSMIC: ISG20L2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143319ENST00000313146Q9H9L3
ENSG00000143319ENST00000368219Q9H9L3

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381531232024Molecular mechanism of human ISG20L2 for the ITS1 cleavage in the processing of 18S precursor ribosomal RNA.0
381531232024Molecular mechanism of human ISG20L2 for the ITS1 cleavage in the processing of 18S precursor ribosomal RNA.0
376469742023ISG20L2: an RNA nuclease regulating T cell activation.0
376469742023ISG20L2: an RNA nuclease regulating T cell activation.0
303948182019High miR-139-3p expression predicts a better prognosis for hepatocellular carcinoma: a pooled analysis.15
303948182019High miR-139-3p expression predicts a better prognosis for hepatocellular carcinoma: a pooled analysis.15
180654032008ISG20L2, a novel vertebrate nucleolar exoribonuclease involved in ribosome biogenesis.26
180654032008ISG20L2, a novel vertebrate nucleolar exoribonuclease involved in ribosome biogenesis.26

Citation

Dessen P

ISG20L2 (interferon stimulated exonuclease gene 20 like 2)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58135/case-report-explorer/gene-explorer/