H4C15 (H4 clustered histone 15)

2019-08-01 Affiliation

Identity

HGNC

H4C15

LOCATION

1q21.2

LOCUSID

554313

ALIAS

H4-16,H4/o,H4C1,H4C11,H4C12,H4C13,H4C14,H4C2,H4C3,H4C4,H4C5,H4C6,H4C8,H4C9,HIST2H4B

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 554313
HGNC: 29607
Ensembl: ENSG00000270276

Variants:

dbSNP: 554313
ClinVar: 554313
TCGA: ENSG00000270276
COSMIC: H4C15

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000270276	ENST00000579512	P62805
ENSG00000270276	ENST00000579512	B2R4R0
ENSG00000270276	ENST00000612061	P62805
ENSG00000270276	ENST00000612061	B2R4R0
ENSG00000270276	ENST00000621520	P62805
ENSG00000270276	ENST00000621520	B2R4R0

Pathways

Pathway	Source	External ID
Systemic lupus erythematosus	KEGG	ko05322
Systemic lupus erythematosus	KEGG	hsa05322
Alcoholism	KEGG	hsa05034
Alcoholism	KEGG	ko05034
Viral carcinogenesis	KEGG	hsa05203
Viral carcinogenesis	KEGG	ko05203
Metabolism of proteins	REACTOME	R-HSA-392499
Amyloid fiber formation	REACTOME	R-HSA-977225
Signal Transduction	REACTOME	R-HSA-162582
Signaling by Rho GTPases	REACTOME	R-HSA-194315
RHO GTPase Effectors	REACTOME	R-HSA-195258
RHO GTPases activate PKNs	REACTOME	R-HSA-5625740
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	REACTOME	R-HSA-5625886
Signaling by Wnt	REACTOME	R-HSA-195721
TCF dependent signaling in response to WNT	REACTOME	R-HSA-201681
Formation of the beta-catenin:TCF transactivating complex	REACTOME	R-HSA-201722
Gene Expression	REACTOME	R-HSA-74160
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription	REACTOME	R-HSA-504046
RNA Polymerase I Transcription	REACTOME	R-HSA-73864
RNA Polymerase I Promoter Clearance	REACTOME	R-HSA-73854
RNA Polymerase I Promoter Opening	REACTOME	R-HSA-73728
RNA Polymerase I Chain Elongation	REACTOME	R-HSA-73777
Gene Silencing by RNA	REACTOME	R-HSA-211000
Transcriptional regulation by small RNAs	REACTOME	R-HSA-5578749
Epigenetic regulation of gene expression	REACTOME	R-HSA-212165
PRC2 methylates histones and DNA	REACTOME	R-HSA-212300
Negative epigenetic regulation of rRNA expression	REACTOME	R-HSA-5250941
SIRT1 negatively regulates rRNA Expression	REACTOME	R-HSA-427359
NoRC negatively regulates rRNA expression	REACTOME	R-HSA-427413
DNA methylation	REACTOME	R-HSA-5334118
Cell Cycle	REACTOME	R-HSA-1640170
Cell Cycle Checkpoints	REACTOME	R-HSA-69620
G2/M Checkpoints	REACTOME	R-HSA-69481
G2/M DNA damage checkpoint	REACTOME	R-HSA-69473
Cell Cycle, Mitotic	REACTOME	R-HSA-69278
M Phase	REACTOME	R-HSA-68886
Mitotic Prophase	REACTOME	R-HSA-68875
Condensation of Prophase Chromosomes	REACTOME	R-HSA-2299718
Chromosome Maintenance	REACTOME	R-HSA-73886
Nucleosome assembly	REACTOME	R-HSA-774815
Deposition of new CENPA-containing nucleosomes at the centromere	REACTOME	R-HSA-606279
Telomere Maintenance	REACTOME	R-HSA-157579
Packaging Of Telomere Ends	REACTOME	R-HSA-171306
Meiosis	REACTOME	R-HSA-1500620
Meiotic recombination	REACTOME	R-HSA-912446
Meiotic synapsis	REACTOME	R-HSA-1221632
Developmental Biology	REACTOME	R-HSA-1266738
DNA Repair	REACTOME	R-HSA-73894
Cellular responses to stress	REACTOME	R-HSA-2262752
Cellular Senescence	REACTOME	R-HSA-2559583
Oxidative Stress Induced Senescence	REACTOME	R-HSA-2559580
DNA Damage/Telomere Stress Induced Senescence	REACTOME	R-HSA-2559586
Senescence-Associated Secretory Phenotype (SASP)	REACTOME	R-HSA-2559582
Chromatin organization	REACTOME	R-HSA-4839726
Chromatin modifying enzymes	REACTOME	R-HSA-3247509
HATs acetylate histones	REACTOME	R-HSA-3214847
HDACs deacetylate histones	REACTOME	R-HSA-3214815
HDMs demethylate histones	REACTOME	R-HSA-3214842
PKMTs methylate histone lysines	REACTOME	R-HSA-3214841
RMTs methylate histone arginines	REACTOME	R-HSA-3214858
DNA Double-Strand Break Repair	REACTOME	R-HSA-5693532
DNA Double Strand Break Response	REACTOME	R-HSA-5693606
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	REACTOME	R-HSA-5693565
Homology Directed Repair	REACTOME	R-HSA-5693538
HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)	REACTOME	R-HSA-5693567
Processing of DNA double-strand break ends	REACTOME	R-HSA-5693607
Nonhomologous End-Joining (NHEJ)	REACTOME	R-HSA-5693571
Positive epigenetic regulation of rRNA expression	REACTOME	R-HSA-5250913
B-WICH complex positively regulates rRNA expression	REACTOME	R-HSA-5250924
Activation of HOX genes during differentiation	REACTOME	R-HSA-5619507
Activation of anterior HOX genes in hindbrain development during early embryogenesis	REACTOME	R-HSA-5617472
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	REACTOME	R-HSA-427389

Citation

Dessen P

H4C15 (H4 clustered histone 15)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58142/h4c15-(h4-clustered-histone-15)

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