Identity
HGNC
LOCATION
5q31.1
LOCUSID
ALIAS
H2A.y,H2A/y,H2AF12M,H2AFY,MACROH2A1.1,mH2A1,macroH2A1.2
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9555
MIM: 610054
HGNC: 4740
Ensembl: ENSG00000113648
Variants:
dbSNP: 9555
ClinVar: 9555
TCGA: ENSG00000113648
COSMIC: MACROH2A1
RNA/Proteins
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Systemic lupus erythematosus | KEGG | ko05322 |
| Systemic lupus erythematosus | KEGG | hsa05322 |
| Alcoholism | KEGG | hsa05034 |
| Alcoholism | KEGG | ko05034 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37852977 | 2023 | MacroH2A1.1 as a crossroad between epigenetics, inflammation and metabolism of mesenchymal stromal cells in myelodysplastic syndromes. | 1 |
| 37852977 | 2023 | MacroH2A1.1 as a crossroad between epigenetics, inflammation and metabolism of mesenchymal stromal cells in myelodysplastic syndromes. | 1 |
| 35072799 | 2022 | Analysis of histone variant constraint and tissue expression suggests five potential novel human disease genes: H2AFY2, H2AFZ, H2AFY, H2AFV, H1F0. | 3 |
| 35472308 | 2022 | High expression of H2A histone family member Y promotes the proliferation and autophagy of hepatocellular carcinoma cells. | 0 |
| 35511867 | 2022 | Histone Variant macroH2A1.1 Enhances Nonhomologous End Joining-dependent DNA Double-strand-break Repair and Reprogramming Efficiency of Human iPSCs. | 9 |
| 35072799 | 2022 | Analysis of histone variant constraint and tissue expression suggests five potential novel human disease genes: H2AFY2, H2AFZ, H2AFY, H2AFV, H1F0. | 3 |
| 35472308 | 2022 | High expression of H2A histone family member Y promotes the proliferation and autophagy of hepatocellular carcinoma cells. | 0 |
| 35511867 | 2022 | Histone Variant macroH2A1.1 Enhances Nonhomologous End Joining-dependent DNA Double-strand-break Repair and Reprogramming Efficiency of Human iPSCs. | 9 |
| 34003252 | 2021 | Poly(ADP-ribose) binding and macroH2A mediate recruitment and functions of KDM5A at DNA lesions. | 15 |
| 34112784 | 2021 | The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation. | 17 |
| 34223906 | 2021 | LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2. | 12 |
| 34887560 | 2021 | Evolution of a histone variant involved in compartmental regulation of NAD metabolism. | 2 |
| 34899687 | 2021 | Exploring the Prognostic Value, Immune Implication and Biological Function of H2AFY Gene in Hepatocellular Carcinoma. | 3 |
| 34003252 | 2021 | Poly(ADP-ribose) binding and macroH2A mediate recruitment and functions of KDM5A at DNA lesions. | 15 |
| 34112784 | 2021 | The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation. | 17 |
Citation
Dessen P
MACROH2A1 (macroH2A.1 histone)
Atlas Genet Cytogenet Oncol Haematol. 2019-08-01
Online version: http://atlasgeneticsoncology.org/gene/58143/macroh2a1-(macroh2a-1-histone)
