Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8777
MIM: 603785
HGNC: 7208
Ensembl: ENSG00000107186
Variants:
dbSNP: 8777
ClinVar: 8777
TCGA: ENSG00000107186
COSMIC: MPDZ
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Tight junction | KEGG | ko04530 |
| Tight junction | KEGG | hsa04530 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37949382 | 2024 | MPDZ is associated with immune infiltration and regulates migration and invasion by switching YAP1 phosphorylation in colorectal cancer. | 0 |
| 37949382 | 2024 | MPDZ is associated with immune infiltration and regulates migration and invasion by switching YAP1 phosphorylation in colorectal cancer. | 0 |
| 36594712 | 2023 | Retinal manifestations in autosomal recessive MPDZ maculopathy: report of two cases and literature review. | 0 |
| 36594712 | 2023 | Retinal manifestations in autosomal recessive MPDZ maculopathy: report of two cases and literature review. | 0 |
| 34135477 | 2022 | ADAMTS1, MPDZ, MVD, and SEZ6: candidate genes for autosomal recessive nonsyndromic hearing impairment. | 6 |
| 35305607 | 2022 | Evaluating the association between MPDZ-NF1B rs1324183 and keratoconus in an independent northwestern Chinese population. | 1 |
| 34135477 | 2022 | ADAMTS1, MPDZ, MVD, and SEZ6: candidate genes for autosomal recessive nonsyndromic hearing impairment. | 6 |
| 35305607 | 2022 | Evaluating the association between MPDZ-NF1B rs1324183 and keratoconus in an independent northwestern Chinese population. | 1 |
| 34108620 | 2021 | MPDZ as a novel epigenetic silenced tumor suppressor inhibits growth and progression of lung cancer through the Hippo-YAP pathway. | 6 |
| 34108620 | 2021 | MPDZ as a novel epigenetic silenced tumor suppressor inhibits growth and progression of lung cancer through the Hippo-YAP pathway. | 6 |
| 31420327 | 2020 | Observation of nine previously reported and 10 non-reported SLC4A11 mutations among 20 Iranian CHED probands and identification of an MPDZ mutation as possible cause of CHED and FECD in one family. | 7 |
| 31420327 | 2020 | Observation of nine previously reported and 10 non-reported SLC4A11 mutations among 20 Iranian CHED probands and identification of an MPDZ mutation as possible cause of CHED and FECD in one family. | 7 |
| 31268831 | 2019 | DAPLE and MPDZ bind to each other and cooperate to promote apical cell constriction. | 14 |
| 31268831 | 2019 | DAPLE and MPDZ bind to each other and cooperate to promote apical cell constriction. | 14 |
| 29620522 | 2018 | MPDZ promotes DLL4-induced Notch signaling during angiogenesis. | 16 |
Citation
Dessen P
MPDZ (multiple PDZ domain crumbs cell polarity complex component)
Atlas Genet Cytogenet Oncol Haematol. 2019-08-01
Online version: http://atlasgeneticsoncology.org/gene/58145/mpdz-(multiple-pdz-domain-crumbs-cell-polarity-complex-component)
