LIMCH1 (LIM and calponin homology domains 1)

2019-08-01  

Identity

HGNC
LOCATION
4p13
LOCUSID
ALIAS
LIMCH1A,LMO7B

Other Information

Locus ID:

NCBI: 22998
MIM: 617750
HGNC: 29191
Ensembl: ENSG00000064042

Variants:

dbSNP: 22998
ClinVar: 22998
TCGA: ENSG00000064042
COSMIC: LIMCH1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000064042ENST00000313860Q9UPQ0
ENSG00000064042ENST00000381753Q9UPQ0
ENSG00000064042ENST00000396595Q9UPQ0
ENSG00000064042ENST00000446625D6R8Y0
ENSG00000064042ENST00000503057G5EA03
ENSG00000064042ENST00000508466H0Y8P3
ENSG00000064042ENST00000508501Q9UPQ0
ENSG00000064042ENST00000509277E9PDJ9
ENSG00000064042ENST00000509454Q6NVB9
ENSG00000064042ENST00000509638D6RJ93
ENSG00000064042ENST00000511424D6RGH8
ENSG00000064042ENST00000511496Q9UPQ0
ENSG00000064042ENST00000512632D6RD46
ENSG00000064042ENST00000512820Q9UPQ0
ENSG00000064042ENST00000512946Q9UPQ0
ENSG00000064042ENST00000513024Q9UPQ0
ENSG00000064042ENST00000514096E7EPK0

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
364446092022LIMCH1 as a New Potential Metastasis Predictor in Breast Cancer.3
364446092022LIMCH1 as a New Potential Metastasis Predictor in Breast Cancer.3
337233902021A 10-gene prognostic signature points to LIMCH1 and HLA-DQB1 as important players in aggressive cervical cancer disease.13
337233902021A 10-gene prognostic signature points to LIMCH1 and HLA-DQB1 as important players in aggressive cervical cancer disease.13
319596242020Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling.22
319596242020Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling.22
312797062019LIMCH1 suppress the growth of lung cancer by interacting with HUWE1 to sustain p53 stability.11
312797062019LIMCH1 suppress the growth of lung cancer by interacting with HUWE1 to sustain p53 stability.11
304290172018LMO7 and LIMCH1 interact with LRIG proteins in lung cancer, with prognostic implications for early-stage disease.15
304290172018LMO7 and LIMCH1 interact with LRIG proteins in lung cancer, with prognostic implications for early-stage disease.15
282285472017LIMCH1 regulates nonmuscle myosin-II activity and suppresses cell migration.34
282285472017LIMCH1 regulates nonmuscle myosin-II activity and suppresses cell migration.34
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

LIMCH1 (LIM and calponin homology domains 1)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58159/cancer-prone-explorer/meetings/