Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7804
MIM: 602600
HGNC: 6700
Ensembl: ENSG00000157193
Variants:
dbSNP: 7804
ClinVar: 7804
TCGA: ENSG00000157193
COSMIC: LRP8
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38263609 | 2024 | LRP8 promotes tumorigenesis in ovarian cancer through inhibiting p53 signaling. | 0 |
| 38281682 | 2024 | The Reelin receptor ApoER2 is a cargo for the adaptor protein complex AP-4: Implications for Hereditary Spastic Paraplegia. | 1 |
| 38389136 | 2024 | MiR-378a-5p exerts a radiosensitizing effect on CRC through LRP8/β-catenin axis. | 0 |
| 38716730 | 2024 | Spon1+ inflammatory monocytes promote collagen remodeling and lung cancer metastasis through lipoprotein receptor 8 signaling. | 0 |
| 38263609 | 2024 | LRP8 promotes tumorigenesis in ovarian cancer through inhibiting p53 signaling. | 0 |
| 38281682 | 2024 | The Reelin receptor ApoER2 is a cargo for the adaptor protein complex AP-4: Implications for Hereditary Spastic Paraplegia. | 1 |
| 38389136 | 2024 | MiR-378a-5p exerts a radiosensitizing effect on CRC through LRP8/β-catenin axis. | 0 |
| 38716730 | 2024 | Spon1+ inflammatory monocytes promote collagen remodeling and lung cancer metastasis through lipoprotein receptor 8 signaling. | 0 |
| 37435859 | 2023 | LRP8-mediated selenocysteine uptake is a targetable vulnerability in MYCN-amplified neuroblastoma. | 10 |
| 38093390 | 2023 | ApoER2-Dab1 disruption as the origin of pTau-associated neurodegeneration in sporadic Alzheimer's disease. | 2 |
| 37435859 | 2023 | LRP8-mediated selenocysteine uptake is a targetable vulnerability in MYCN-amplified neuroblastoma. | 10 |
| 38093390 | 2023 | ApoER2-Dab1 disruption as the origin of pTau-associated neurodegeneration in sporadic Alzheimer's disease. | 2 |
| 31994910 | 2022 | LRP8, modulated by miR-1262, promotes tumour progression and forecasts the prognosis of patients in breast cancer. | 6 |
| 35414534 | 2022 | Human APOER2 Isoforms Have Differential Cleavage Events and Synaptic Properties. | 7 |
| 31994910 | 2022 | LRP8, modulated by miR-1262, promotes tumour progression and forecasts the prognosis of patients in breast cancer. | 6 |
Citation
Dessen P
LRP8 (LDL receptor related protein 8)
Atlas Genet Cytogenet Oncol Haematol. 2021-06-01
Online version: http://atlasgeneticsoncology.org/gene/58182/submit-meetings/
