ANKZF1 (ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1)

2021-06-01  

Identity

HGNC
LOCATION
2q35
LOCUSID
ALIAS
Vms1,ZNF744

Other Information

Locus ID:

NCBI: 55139
MIM: 617541
HGNC: 25527
Ensembl: ENSG00000163516

Variants:

dbSNP: 55139
ClinVar: 55139
TCGA: ENSG00000163516
COSMIC: ANKZF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163516ENST00000323348Q9H8Y5
ENSG00000163516ENST00000323348A0A024R464
ENSG00000163516ENST00000409849B8ZZS4
ENSG00000163516ENST00000410034Q9H8Y5
ENSG00000163516ENST00000410034A0A024R464
ENSG00000163516ENST00000416565C9J5H7
ENSG00000163516ENST00000435521F8WD44
ENSG00000163516ENST00000436226C9JQZ3
ENSG00000163516ENST00000447157C9K022
ENSG00000163516ENST00000453432C9JS61

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
296323122018Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes.22
302448312018Release of Ubiquitinated and Non-ubiquitinated Nascent Chains from Stalled Mammalian Ribosomal Complexes by ANKZF1 and Ptrh1.17
283027252017Ankyrin repeat and zinc-finger domain-containing 1 mutations are associated with infantile-onset inflammatory bowel disease.3
312579222019High ANKZF1 expression is associated with poor overall survival and recurrence-free survival in colon cancer.1

Citation

Dessen P

ANKZF1 (ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58191/ankzf1-(ankyrin-repeat-and-zinc-finger-peptidyl-trna-hydrolase-1)