Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4720
MIM: 602985
HGNC: 7708
Ensembl: ENSG00000158864
Variants:
dbSNP: 4720
ClinVar: 4720
TCGA: ENSG00000158864
COSMIC: NDUFS2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000158864 | ENST00000367993 | O75306 |
| ENSG00000158864 | ENST00000392179 | O75306 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38195952 | 2024 | NUDT21 interacts with NDUFS2 to activate the PI3K/AKT pathway and promotes pancreatic cancer pathogenesis. | 0 |
| 38195952 | 2024 | NUDT21 interacts with NDUFS2 to activate the PI3K/AKT pathway and promotes pancreatic cancer pathogenesis. | 0 |
| 33744462 | 2021 | Complex I protein NDUFS2 is vital for growth, ROS generation, membrane integrity, apoptosis, and mitochondrial energetics. | 10 |
| 33744462 | 2021 | Complex I protein NDUFS2 is vital for growth, ROS generation, membrane integrity, apoptosis, and mitochondrial energetics. | 10 |
| 30885944 | 2019 | S100A4 alters metabolism and promotes invasion of lung cancer cells by up-regulating mitochondrial complex I protein NDUFS2. | 36 |
| 30885944 | 2019 | S100A4 alters metabolism and promotes invasion of lung cancer cells by up-regulating mitochondrial complex I protein NDUFS2. | 36 |
| 28031252 | 2017 | Compound heterozygosity for severe and hypomorphic NDUFS2 mutations cause non-syndromic LHON-like optic neuropathy. | 24 |
| 28031252 | 2017 | Compound heterozygosity for severe and hypomorphic NDUFS2 mutations cause non-syndromic LHON-like optic neuropathy. | 24 |
| 26053550 | 2015 | Do nuclear-encoded core subunits of mitochondrial complex I confer genetic susceptibility to schizophrenia in Han Chinese populations? | 4 |
| 26053550 | 2015 | Do nuclear-encoded core subunits of mitochondrial complex I confer genetic susceptibility to schizophrenia in Han Chinese populations? | 4 |
| 23266820 | 2013 | Leigh syndrome associated with mitochondrial complex I deficiency due to novel mutations In NDUFV1 and NDUFS2. | 14 |
| 24089531 | 2013 | NDUFAF7 methylates arginine 85 in the NDUFS2 subunit of human complex I. | 48 |
| 23266820 | 2013 | Leigh syndrome associated with mitochondrial complex I deficiency due to novel mutations In NDUFV1 and NDUFS2. | 14 |
| 24089531 | 2013 | NDUFAF7 methylates arginine 85 in the NDUFS2 subunit of human complex I. | 48 |
| 22036843 | 2012 | A catalytic defect in mitochondrial respiratory chain complex I due to a mutation in NDUFS2 in a patient with Leigh syndrome. | 14 |
Citation
Dessen P
NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2)
Atlas Genet Cytogenet Oncol Haematol. 2021-06-01
Online version: http://atlasgeneticsoncology.org/gene/58194/ndufs2-(nadh-ubiquinone-oxidoreductase-core-subunit-s2)
