Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9453
MIM: 606982
HGNC: 4249
Ensembl: ENSG00000152904
Variants:
dbSNP: 9453
ClinVar: 9453
TCGA: ENSG00000152904
COSMIC: GGPS1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36650113 | 2023 | Geranylgeranyl diphosphate synthase: Role in human health, disease and potential therapeutic target. | 4 |
| 36650113 | 2023 | Geranylgeranyl diphosphate synthase: Role in human health, disease and potential therapeutic target. | 4 |
| 35334098 | 2022 | Knockout of GGPPS1 restrains rab37-mediated autophagy in response to ventilator-induced lung injury. | 1 |
| 35869884 | 2022 | GGPS1-associated muscular dystrophy with and without hearing loss. | 2 |
| 35334098 | 2022 | Knockout of GGPPS1 restrains rab37-mediated autophagy in response to ventilator-induced lung injury. | 1 |
| 35869884 | 2022 | GGPS1-associated muscular dystrophy with and without hearing loss. | 2 |
| 33587247 | 2021 | The Genetics of Atypical Femur Fractures-a Systematic Review. | 10 |
| 33587247 | 2021 | The Genetics of Atypical Femur Fractures-a Systematic Review. | 10 |
| 32399598 | 2020 | Genomic sequencing highlights the diverse molecular causes of Perrault syndrome: a peroxisomal disorder (PEX6), metabolic disorders (CLPP, GGPS1), and mtDNA maintenance/translation disorders (LARS2, TFAM). | 17 |
| 32403198 | 2020 | GGPS1 Mutations Cause Muscular Dystrophy/Hearing Loss/Ovarian Insufficiency Syndrome. | 15 |
| 32399598 | 2020 | Genomic sequencing highlights the diverse molecular causes of Perrault syndrome: a peroxisomal disorder (PEX6), metabolic disorders (CLPP, GGPS1), and mtDNA maintenance/translation disorders (LARS2, TFAM). | 17 |
| 32403198 | 2020 | GGPS1 Mutations Cause Muscular Dystrophy/Hearing Loss/Ovarian Insufficiency Syndrome. | 15 |
| 29377583 | 2018 | Overexpression of geranylgeranyl diphosphate synthase contributes to tumour metastasis and correlates with poor prognosis of lung adenocarcinoma. | 12 |
| 30184270 | 2018 | Functional Characterization of a GGPPS Variant Identified in Atypical Femoral Fracture Patients and Delineation of the Role of GGPPS in Bone-Relevant Cell Types. | 11 |
| 29377583 | 2018 | Overexpression of geranylgeranyl diphosphate synthase contributes to tumour metastasis and correlates with poor prognosis of lung adenocarcinoma. | 12 |
Citation
Dessen P
GGPS1 (geranylgeranyl diphosphate synthase 1)
Atlas Genet Cytogenet Oncol Haematol. 2021-06-01
Online version: http://atlasgeneticsoncology.org/gene/58195/ggps1-(geranylgeranyl-diphosphate-synthase-1)
