TMX1 (thioredoxin related transmembrane protein 1)

2021-06-01  

Identity

HGNC
LOCATION
14q22.1
LOCUSID
ALIAS
PDIA11,TMX,TXNDC,TXNDC1

Other Information

Locus ID:

NCBI: 81542
MIM: 610527
HGNC: 15487
Ensembl: ENSG00000139921

Variants:

dbSNP: 81542
ClinVar: 81542
TCGA: ENSG00000139921
COSMIC: TMX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139921ENST00000457354Q9H3N1
ENSG00000139921ENST00000556683G3V448

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381470242023TMX family genes and their association with prognosis, immune infiltration, and chemotherapy in human pan-cancer.0
381470242023TMX family genes and their association with prognosis, immune infiltration, and chemotherapy in human pan-cancer.0
339409442021Thiol Isomerases Orchestrate Thrombosis and Hemostasis.7
339409442021Thiol Isomerases Orchestrate Thrombosis and Hemostasis.7
313049842019Redox signals at the ER-mitochondria interface control melanoma progression.33
313049842019Redox signals at the ER-mitochondria interface control melanoma progression.33
299329152018The reductase TMX1 contributes to ERAD by preferentially acting on membrane-associated folding-defective polypeptides.8
299329152018The reductase TMX1 contributes to ERAD by preferentially acting on membrane-associated folding-defective polypeptides.8
275024842016TMX1 determines cancer cell metabolism as a thiol-based modulator of ER-mitochondria Ca2+ flux.60
275024842016TMX1 determines cancer cell metabolism as a thiol-based modulator of ER-mitochondria Ca2+ flux.60
262466042015Division of labor among oxidoreductases: TMX1 preferentially acts on transmembrane polypeptides.15
262466042015Division of labor among oxidoreductases: TMX1 preferentially acts on transmembrane polypeptides.15
229248222013The protective role of the transmembrane thioredoxin-related protein TMX in inflammatory liver injury.9
229248222013The protective role of the transmembrane thioredoxin-related protein TMX in inflammatory liver injury.9
220453382012Palmitoylated TMX and calnexin target to the mitochondria-associated membrane.108

Citation

Dessen P

TMX1 (thioredoxin related transmembrane protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58205/tmx1-(thioredoxin-related-transmembrane-protein-1)