Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 78999
MIM: 612810
HGNC: 28456
Ensembl: ENSG00000173621
Variants:
dbSNP: 78999
ClinVar: 78999
TCGA: ENSG00000173621
COSMIC: LRFN4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000173621 | ENST00000309602 | Q6PJG9 |
| ENSG00000173621 | ENST00000309602 | A0A024R5I6 |
| ENSG00000173621 | ENST00000393952 | E7ENX6 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuronal System | REACTOME | R-HSA-112316 |
| SALM protein interactions at the synapses | REACTOME | R-HSA-8849932 |
| Protein-protein interactions at synapses | REACTOME | R-HSA-6794362 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32536098 | 2020 | [Expression and clinical significance of LRFN4 in colorectal cancer tissue]. | 3 |
| 32536098 | 2020 | [Expression and clinical significance of LRFN4 in colorectal cancer tissue]. | 3 |
| 31089399 | 2019 | High SALM3 Expression in Tumor Cells and Fibroblasts Is Correlated with Poor Prognosis in Gastric Cancer Patients. | 6 |
| 31089399 | 2019 | High SALM3 Expression in Tumor Cells and Fibroblasts Is Correlated with Poor Prognosis in Gastric Cancer Patients. | 6 |
| 26321637 | 2015 | Splicing-Dependent Trans-synaptic SALM3-LAR-RPTP Interactions Regulate Excitatory Synapse Development and Locomotion. | 40 |
| 26321637 | 2015 | Splicing-Dependent Trans-synaptic SALM3-LAR-RPTP Interactions Regulate Excitatory Synapse Development and Locomotion. | 40 |
| 22677168 | 2012 | A neuronal transmembrane protein LRFN4 complexes with 14-3-3s and NCK1 to induce morphological change in monocytic cells via Rac1-mediated actin cytoskeleton reorganization. | 8 |
| 22677168 | 2012 | A neuronal transmembrane protein LRFN4 complexes with 14-3-3s and NCK1 to induce morphological change in monocytic cells via Rac1-mediated actin cytoskeleton reorganization. | 8 |
| 21704618 | 2011 | A neuronal transmembrane protein LRFN4 induces monocyte/macrophage migration via actin cytoskeleton reorganization. | 9 |
| 21704618 | 2011 | A neuronal transmembrane protein LRFN4 induces monocyte/macrophage migration via actin cytoskeleton reorganization. | 9 |
Citation
Dessen P
LRFN4 (leucine rich repeat and fibronectin type III domain containing 4)
Atlas Genet Cytogenet Oncol Haematol. 2021-06-01
Online version: http://atlasgeneticsoncology.org/gene/58231/lrfn4-(leucine-rich-repeat-and-fibronectin-type-iii-domain-containing-4)
