Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 652968
MIM: 617034
HGNC: 34423
Ensembl: ENSG00000239282
Variants:
dbSNP: 652968
ClinVar: 652968
TCGA: ENSG00000239282
COSMIC: CASTOR1
RNA/Proteins
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33594058 | 2021 | RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation. | 13 |
| 33594058 | 2021 | RNF167 activates mTORC1 and promotes tumorigenesis by targeting CASTOR1 for ubiquitination and degradation. | 13 |
| 30503338 | 2019 | Crystal structures of arginine sensor CASTOR1 in arginine-bound and ligand free states. | 4 |
| 31305263 | 2019 | Kaposi sarcoma-associated herpesvirus miRNAs suppress CASTOR1-mediated mTORC1 inhibition to promote tumorigenesis. | 21 |
| 31659101 | 2019 | Seeking mTORC1 Inhibitors Through Molecular Dynamics Simulation of Arginine Analogs Inhibiting CASTOR1. | 3 |
| 30503338 | 2019 | Crystal structures of arginine sensor CASTOR1 in arginine-bound and ligand free states. | 4 |
| 31305263 | 2019 | Kaposi sarcoma-associated herpesvirus miRNAs suppress CASTOR1-mediated mTORC1 inhibition to promote tumorigenesis. | 21 |
| 31659101 | 2019 | Seeking mTORC1 Inhibitors Through Molecular Dynamics Simulation of Arginine Analogs Inhibiting CASTOR1. | 3 |
| 30132978 | 2018 | CASTOR1 suppresses the progression of lung adenocarcinoma and predicts poor prognosis. | 3 |
| 30132978 | 2018 | CASTOR1 suppresses the progression of lung adenocarcinoma and predicts poor prognosis. | 3 |
| 26972053 | 2016 | The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway. | 380 |
| 27487210 | 2016 | Mechanism of arginine sensing by CASTOR1 upstream of mTORC1. | 144 |
| 26972053 | 2016 | The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway. | 380 |
| 27487210 | 2016 | Mechanism of arginine sensing by CASTOR1 upstream of mTORC1. | 144 |
| 24449572 | 2014 | Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study. | 24 |
Citation
Dessen P
CASTOR1 (cytosolic arginine sensor for mTORC1 subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2021-06-01
Online version: http://atlasgeneticsoncology.org/gene/58240/teaching-explorer/submit-meetings/
