Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51143
MIM: 615890
HGNC: 18745
Ensembl: ENSG00000144635
Variants:
dbSNP: 51143
ClinVar: 51143
TCGA: ENSG00000144635
COSMIC: DYNC1LI1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000144635 | ENST00000273130 | Q9Y6G9 |
| ENSG00000144635 | ENST00000413350 | C9JGM7 |
| ENSG00000144635 | ENST00000424991 | C9JLW1 |
| ENSG00000144635 | ENST00000432458 | E9PHI6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34709360 | 2021 | Phosphorylation and Pin1 binding to the LIC1 subunit selectively regulate mitotic dynein functions. | 5 |
| 34709360 | 2021 | Phosphorylation and Pin1 binding to the LIC1 subunit selectively regulate mitotic dynein functions. | 5 |
| 32319648 | 2020 | Association between aberrant dynein cytoplasmic 1 light intermediate chain 1 expression levels, mucins and chemosensitivity in colorectal cancer. | 7 |
| 32513296 | 2020 | Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes. | 37 |
| 32319648 | 2020 | Association between aberrant dynein cytoplasmic 1 light intermediate chain 1 expression levels, mucins and chemosensitivity in colorectal cancer. | 7 |
| 32513296 | 2020 | Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes. | 37 |
| 30657258 | 2019 | DLIC1, but not DLIC2, is upregulated in colon cancer and this contributes to proliferative overgrowth and migratory characteristics of cancer cells. | 7 |
| 30657258 | 2019 | DLIC1, but not DLIC2, is upregulated in colon cancer and this contributes to proliferative overgrowth and migratory characteristics of cancer cells. | 7 |
| 29515126 | 2018 | A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity. | 53 |
| 29515126 | 2018 | A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity. | 53 |
| 27482052 | 2016 | Assembly and activation of dynein-dynactin by the cargo adaptor protein Hook3. | 76 |
| 27510948 | 2016 | Cellular model of neuronal atrophy induced by DYNC1I1 deficiency reveals protective roles of RAS-RAF-MEK signaling. | 10 |
| 27482052 | 2016 | Assembly and activation of dynein-dynactin by the cargo adaptor protein Hook3. | 76 |
| 27510948 | 2016 | Cellular model of neuronal atrophy induced by DYNC1I1 deficiency reveals protective roles of RAS-RAF-MEK signaling. | 10 |
| 25422374 | 2014 | Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion. | 15 |
Citation
Dessen P
DYNC1LI1 (dynein cytoplasmic 1 light intermediate chain 1)
Atlas Genet Cytogenet Oncol Haematol. 2021-06-01
Online version: http://atlasgeneticsoncology.org/gene/58296/dync1li1-(dynein-cytoplasmic-1-light-intermediate-chain-1)
