RPRD1A (regulation of nuclear pre-mRNA domain containing 1A)

2021-06-01  

Identity

HGNC
LOCATION
18q12.2
LOCUSID
ALIAS
HsT3101,P15RS

Other Information

Locus ID:

NCBI: 55197
MIM: 610347
HGNC: 25560
Ensembl: ENSG00000141425

Variants:

dbSNP: 55197
ClinVar: 55197
TCGA: ENSG00000141425
COSMIC: RPRD1A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000141425ENST00000357384Q96P16
ENSG00000141425ENST00000357384A0A024RC37
ENSG00000141425ENST00000399022Q96P16
ENSG00000141425ENST00000399022A0A024RC37
ENSG00000141425ENST00000585953K7EP82
ENSG00000141425ENST00000587563K7ER50
ENSG00000141425ENST00000588737Q96P16
ENSG00000141425ENST00000589050A0A0C4DGQ6
ENSG00000141425ENST00000590898Q96P16
ENSG00000141425ENST00000592674K7EQR8

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA polymerase II transcribes snRNA genesREACTOMER-HSA-6807505

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
349211372021RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding.8
349211372021RPRD1A stabilizes NRF2 and aggravates HCC progression through competing with p62 for TRIM21 binding.8
308092862019MiR-454-3p-Mediated Wnt/β-catenin Signaling Antagonists Suppression Promotes Breast Cancer Metastasis.62
308092862019MiR-454-3p-Mediated Wnt/β-catenin Signaling Antagonists Suppression Promotes Breast Cancer Metastasis.62
256973592015p15RS/RPRD1A (p15INK4b-related sequence/regulation of nuclear pre-mRNA domain-containing protein 1A) interacts with HDAC2 in inhibition of the Wnt/β-catenin signaling pathway.23
256973592015p15RS/RPRD1A (p15INK4b-related sequence/regulation of nuclear pre-mRNA domain-containing protein 1A) interacts with HDAC2 in inhibition of the Wnt/β-catenin signaling pathway.23
249976002014RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.55
249976002014RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.55
225804562012Cellular and molecular evidence for malignancy-inhibitory functions of p15RS.7
225804562012Cellular and molecular evidence for malignancy-inhibitory functions of p15RS.7
207392732010p15RS attenuates Wnt/{beta}-catenin signaling by disrupting {beta}-catenin·TCF4 Interaction.19
207392732010p15RS attenuates Wnt/{beta}-catenin signaling by disrupting {beta}-catenin·TCF4 Interaction.19
124706612002Identification and characterization of P15RS, a novel P15(INK4b) related gene on G1/S progression.10
124706612002Identification and characterization of P15RS, a novel P15(INK4b) related gene on G1/S progression.10

Citation

Dessen P

RPRD1A (regulation of nuclear pre-mRNA domain containing 1A)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58297/rprd1a-(regulation-of-nuclear-pre-mrna-domain-containing-1a)