CAMSAP3 (calmodulin regulated spectrin associated protein family member 3)

2021-06-01  

Identity

HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
KIAA1543,NEZHA,PPP1R80

Other Information

Locus ID:

NCBI: 57662
MIM: 612685
HGNC: 29307
Ensembl: ENSG00000076826

Variants:

dbSNP: 57662
ClinVar: 57662
TCGA: ENSG00000076826
COSMIC: CAMSAP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000076826ENST00000160298Q9P1Y5
ENSG00000076826ENST00000446248Q9P1Y5

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
190417552008Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts.140
195089792009The CKK domain (DUF1781) binds microtubules and defines the CAMSAP/ssp4 family of animal proteins.35
267157422016CAMSAP3 orients the apical-to-basal polarity of microtubule arrays in epithelial cells.30
278021682016Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7.22
276935092016The CAMSAP3-ACF7 Complex Couples Noncentrosomal Microtubules with Actin Filaments to Coordinate Their Dynamics.13
273491802016Cadherin 23-C Regulates Microtubule Networks by Modifying CAMSAP3's Function.5
280893912017CAMSAP3-dependent microtubule dynamics regulates Golgi assembly in epithelial cells.3
302826322018Loss of CAMSAP3 promotes EMT via the modification of microtubule-Akt machinery.2

Citation

Dessen P

CAMSAP3 (calmodulin regulated spectrin associated protein family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58306/camsap3-(calmodulin-regulated-spectrin-associated-protein-family-member-3)