Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8443
MIM: 602744
HGNC: 4416
Ensembl: ENSG00000116906
Variants:
dbSNP: 8443
ClinVar: 8443
TCGA: ENSG00000116906
COSMIC: GNPAT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000116906 | ENST00000366647 | O15228 |
| ENSG00000116906 | ENST00000416000 | Q5TBH8 |
| ENSG00000116906 | ENST00000436239 | Q5TBH6 |
| ENSG00000116906 | ENST00000644483 | A0A2R8YH69 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36161951 | 2022 | Genetic adaptation of skin pigmentation in highland Tibetans. | 3 |
| 36161951 | 2022 | Genetic adaptation of skin pigmentation in highland Tibetans. | 3 |
| 31974474 | 2020 | Stabilization of FASN by ACAT1-mediated GNPAT acetylation promotes lipid metabolism and hepatocarcinogenesis. | 56 |
| 32652459 | 2020 | Increased frequency of GNPAT p.D519G in compound HFE p.C282Y/p.H63D heterozygotes with elevated serum ferritin levels. | 2 |
| 31974474 | 2020 | Stabilization of FASN by ACAT1-mediated GNPAT acetylation promotes lipid metabolism and hepatocarcinogenesis. | 56 |
| 32652459 | 2020 | Increased frequency of GNPAT p.D519G in compound HFE p.C282Y/p.H63D heterozygotes with elevated serum ferritin levels. | 2 |
| 30143522 | 2018 | Amplification of Glyceronephosphate O-Acyltransferase and Recruitment of USP30 Stabilize DRP1 to Promote Hepatocarcinogenesis. | 27 |
| 30143522 | 2018 | Amplification of Glyceronephosphate O-Acyltransferase and Recruitment of USP30 Stabilize DRP1 to Promote Hepatocarcinogenesis. | 27 |
| 27936396 | 2017 | GNPAT p.D519G is independently associated with markedly increased iron stores in HFE p.C282Y homozygotes. | 8 |
| 28292831 | 2017 | Reduction of Ether-Type Glycerophospholipids, Plasmalogens, by NF-κB Signal Leading to Microglial Activation. | 15 |
| 28425416 | 2017 | GNPAT rs11558492 is not a Major Modifier of Iron Status: Study of Italian Hemochromatosis Patients and Blood Donors. | 9 |
| 27936396 | 2017 | GNPAT p.D519G is independently associated with markedly increased iron stores in HFE p.C282Y homozygotes. | 8 |
| 28292831 | 2017 | Reduction of Ether-Type Glycerophospholipids, Plasmalogens, by NF-κB Signal Leading to Microglial Activation. | 15 |
| 28425416 | 2017 | GNPAT rs11558492 is not a Major Modifier of Iron Status: Study of Italian Hemochromatosis Patients and Blood Donors. | 9 |
| 27740525 | 2016 | GNPAT variant (D519G) is not associated with an elevated serum ferritin or iron removed by phlebotomy in patients referred for C282Y-linked hemochromatosis. | 4 |
Citation
Dessen P
GNPAT (glyceronephosphate O-acyltransferase)
Atlas Genet Cytogenet Oncol Haematol. 2021-06-01
Online version: http://atlasgeneticsoncology.org/gene/58335/gnpat-(glyceronephosphate-o-acyltransferase)
