Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 135892
MIM: 612548
HGNC: 19017
Ensembl: ENSG00000146755
Variants:
dbSNP: 135892
ClinVar: 135892
TCGA: ENSG00000146755
COSMIC: TRIM50
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000146755 | ENST00000333149 | Q86XT4 |
| ENSG00000146755 | ENST00000333149 | Q2M204 |
| ENSG00000146755 | ENST00000453152 | Q86XT4 |
| ENSG00000146755 | ENST00000453152 | Q2M204 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37409971 | 2023 | TRIM50 Inhibits Gastric Cancer Progression by Regulating the Ubiquitination and Nuclear Translocation of JUP. | 2 |
| 37409971 | 2023 | TRIM50 Inhibits Gastric Cancer Progression by Regulating the Ubiquitination and Nuclear Translocation of JUP. | 2 |
| 29604308 | 2018 | TRIM50 regulates Beclin 1 proautophagic activity. | 27 |
| 29789583 | 2018 | TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation. | 24 |
| 29604308 | 2018 | TRIM50 regulates Beclin 1 proautophagic activity. | 27 |
| 29789583 | 2018 | TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation. | 24 |
| 24308962 | 2014 | HDAC6 mediates the acetylation of TRIM50. | 10 |
| 24308962 | 2014 | HDAC6 mediates the acetylation of TRIM50. | 10 |
| 22792322 | 2012 | The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome. | 34 |
| 22792322 | 2012 | The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome. | 34 |
| 18398435 | 2008 | Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase. | 26 |
| 18398435 | 2008 | Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase. | 26 |
Citation
Dessen P
TRIM50 (tripartite motif containing 50)
Atlas Genet Cytogenet Oncol Haematol. 2021-06-01
Online version: http://atlasgeneticsoncology.org/gene/58338/trim50-(tripartite-motif-containing-50)
