POLR3GL (RNA polymerase III subunit GL)

2021-06-01  

Identity

HGNC
LOCATION
1q21.1
LOCUSID
ALIAS
RPC32HOM,SOFM,flj32422

Other Information

Locus ID:

NCBI: 84265
MIM: 617457
HGNC: 28466
Ensembl: ENSG00000121851

Variants:

dbSNP: 84265
ClinVar: 84265
TCGA: ENSG00000121851
COSMIC: POLR3GL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121851ENST00000369313A6NGX6
ENSG00000121851ENST00000369314Q9BT43

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Pyrimidine metabolismKEGGko00240
RNA polymeraseKEGGko03020
Purine metabolismKEGGhsa00230
Pyrimidine metabolismKEGGhsa00240
RNA polymeraseKEGGhsa03020
Cytosolic DNA-sensing pathwayKEGGko04623
Cytosolic DNA-sensing pathwayKEGGhsa04623
Metabolic pathwaysKEGGhsa01100
RNA polymerase III, eukaryotesKEGGhsa_M00181
Epstein-Barr virus infectionKEGGhsa05169
Epstein-Barr virus infectionKEGGko05169
RNA polymerase III, eukaryotesKEGGM00181
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Cytosolic sensors of pathogen-associated DNAREACTOMER-HSA-1834949
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionREACTOMER-HSA-504046
RNA Polymerase III TranscriptionREACTOMER-HSA-74158
RNA Polymerase III Abortive And Retractive InitiationREACTOMER-HSA-749476
RNA Polymerase III Transcription InitiationREACTOMER-HSA-76046
RNA Polymerase III Transcription Initiation From Type 1 PromoterREACTOMER-HSA-76061
RNA Polymerase III Transcription Initiation From Type 2 PromoterREACTOMER-HSA-76066
RNA Polymerase III Transcription Initiation From Type 3 PromoterREACTOMER-HSA-76071
RNA Polymerase III Chain ElongationREACTOMER-HSA-73780
RNA Polymerase III Transcription TerminationREACTOMER-HSA-73980

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
335587662021Structural insights into transcriptional regulation of human RNA polymerase III.20
335587662021Structural insights into transcriptional regulation of human RNA polymerase III.20
308205482019Effects on prostate cancer cells of targeting RNA polymerase III.22
308205482019Effects on prostate cancer cells of targeting RNA polymerase III.22

Citation

Dessen P

POLR3GL (RNA polymerase III subunit GL)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58361/polr3gl-(rna-polymerase-iii-subunit-gl)