STXBP5 (syntaxin binding protein 5)

2021-06-01  

Identity

HGNC
LOCATION
6q24.3
LOCUSID
ALIAS
LGL3,LLGL3,Nbla04300

Other Information

Locus ID:

NCBI: 134957
MIM: 604586
HGNC: 19665
Ensembl: ENSG00000164506

Variants:

dbSNP: 134957
ClinVar: 134957
TCGA: ENSG00000164506
COSMIC: STXBP5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164506ENST00000321680Q5T5C0
ENSG00000164506ENST00000367475H0Y332
ENSG00000164506ENST00000367480Q5T5C0
ENSG00000164506ENST00000367481Q5T5C0
ENSG00000164506ENST00000392291Q5JRH0
ENSG00000164506ENST00000546097Q3B794

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
339653772021Aberrant hypermethylation induced downregulation of antisense lncRNA STXBP5-AS1 and its sense gene STXBP5 correlate with tumorigenesis of glioma.3
339653772021Aberrant hypermethylation induced downregulation of antisense lncRNA STXBP5-AS1 and its sense gene STXBP5 correlate with tumorigenesis of glioma.3
328517332020Genetic evidence for an inhibitory role of tomosyn in insulin-stimulated GLUT4 exocytosis.8
328517332020Genetic evidence for an inhibitory role of tomosyn in insulin-stimulated GLUT4 exocytosis.8
312019482019Interaction networks of Weibel-Palade body regulators syntaxin-3 and syntaxin binding protein 5 in endothelial cells.3
312121312019LncRNA STXBP5-AS1 suppressed cervical cancer progression via targeting miR-96-5p/PTEN axis.32
312019482019Interaction networks of Weibel-Palade body regulators syntaxin-3 and syntaxin binding protein 5 in endothelial cells.3
312121312019LncRNA STXBP5-AS1 suppressed cervical cancer progression via targeting miR-96-5p/PTEN axis.32
294852002018Tomosyn guides SNARE complex formation in coordination with Munc18 and Munc13.12
299706022018Tomosyn functions as a PKCδ-regulated fusion clamp in mast cell degranulation.5
299728632018Genetic Variation in the Syntaxin-Binding Protein STXBP5 in Type 1 von Willebrand Disease Patients.5
294852002018Tomosyn guides SNARE complex formation in coordination with Munc18 and Munc13.12
299706022018Tomosyn functions as a PKCδ-regulated fusion clamp in mast cell degranulation.5
299728632018Genetic Variation in the Syntaxin-Binding Protein STXBP5 in Type 1 von Willebrand Disease Patients.5
280624982017Novel Thrombotic Function of a Human SNP in STXBP5 Revealed by CRISPR/Cas9 Gene Editing in Mice.13

Citation

Dessen P

STXBP5 (syntaxin binding protein 5)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58371/stxbp5-(syntaxin-binding-protein-5)