Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 18
MIM: 137150
HGNC: 23
Ensembl: ENSG00000183044
Variants:
dbSNP: 18
ClinVar: 18
TCGA: ENSG00000183044
COSMIC: ABAT
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA451846 | valproic acid | Chemical | Pathway | associated | 23407051 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36718958 | 2023 | Effects of UGT1A, CYP2C9/19 and ABAT polymorphisms on plasma concentration of valproic acid in Chinese epilepsy patients. | 0 |
| 37122729 | 2023 | A crucial exosome-related gene pair (AAMP and ABAT) is associated with inflammatory cells in intervertebral disc degeneration. | 1 |
| 36718958 | 2023 | Effects of UGT1A, CYP2C9/19 and ABAT polymorphisms on plasma concentration of valproic acid in Chinese epilepsy patients. | 0 |
| 37122729 | 2023 | A crucial exosome-related gene pair (AAMP and ABAT) is associated with inflammatory cells in intervertebral disc degeneration. | 1 |
| 33404980 | 2021 | Exploring the Genetic Association of the ABAT Gene with Alzheimer's Disease. | 4 |
| 34742920 | 2021 | ABAT targeted by miR-183-5p regulates cell functions in liver cancer. | 8 |
| 33404980 | 2021 | Exploring the Genetic Association of the ABAT Gene with Alzheimer's Disease. | 4 |
| 34742920 | 2021 | ABAT targeted by miR-183-5p regulates cell functions in liver cancer. | 8 |
| 30277654 | 2018 | Gamma-aminobutyric acid transaminase genetic polymorphism is a candidate locus for responsiveness to opioid analgesics in patients with cancer pain: An exploratory study. | 7 |
| 30277654 | 2018 | Gamma-aminobutyric acid transaminase genetic polymorphism is a candidate locus for responsiveness to opioid analgesics in patients with cancer pain: An exploratory study. | 7 |
| 25771305 | 2015 | Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease. | 33 |
| 25771305 | 2015 | Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease. | 33 |
| 25485164 | 2014 | Disorders of GABA metabolism: SSADH and GABA-transaminase deficiencies. | 29 |
| 25485164 | 2014 | Disorders of GABA metabolism: SSADH and GABA-transaminase deficiencies. | 29 |
| 22225676 | 2013 | Variants within the GABA transaminase (ABAT) gene region are associated with somatosensory evoked EEG potentials in families at high risk for affective disorders. | 3 |
Citation
Dessen P
ABAT (4-aminobutyrate aminotransferase)
Atlas Genet Cytogenet Oncol Haematol. 2021-06-01
Online version: http://atlasgeneticsoncology.org/gene/58380/abat-(4-aminobutyrate-aminotransferase)
