Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84706
MIM: 138210
HGNC: 18062
Ensembl: ENSG00000166123
Variants:
dbSNP: 84706
ClinVar: 84706
TCGA: ENSG00000166123
COSMIC: GPT2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166123 | ENST00000340124 | Q8TD30 |
| ENSG00000166123 | ENST00000340124 | A0A024R6R2 |
| ENSG00000166123 | ENST00000440783 | Q8TD30 |
| ENSG00000166123 | ENST00000562132 | H3BU54 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36923530 | 2023 | The delta subunit of the GABA(A) receptor is necessary for the GPT2-promoted breast cancer metastasis. | 2 |
| 37287397 | 2023 | Exosomal GPT2 derived from triple-negative breast cancer cells promotes metastasis by activating BTRC. | 1 |
| 36923530 | 2023 | The delta subunit of the GABA(A) receptor is necessary for the GPT2-promoted breast cancer metastasis. | 2 |
| 37287397 | 2023 | Exosomal GPT2 derived from triple-negative breast cancer cells promotes metastasis by activating BTRC. | 1 |
| 35196498 | 2022 | Thyroid hormone regulates glutamine metabolism and anaplerotic fluxes by inducing mitochondrial glutamate aminotransferase GPT2. | 5 |
| 35908744 | 2022 | Loss of mitochondrial enzyme GPT2 causes early neurodegeneration in locus coeruleus. | 2 |
| 36527113 | 2022 | SPTBN1 abrogates renal clear cell carcinoma progression via glycolysis reprogramming in a GPT2-dependent manner. | 4 |
| 35196498 | 2022 | Thyroid hormone regulates glutamine metabolism and anaplerotic fluxes by inducing mitochondrial glutamate aminotransferase GPT2. | 5 |
| 35908744 | 2022 | Loss of mitochondrial enzyme GPT2 causes early neurodegeneration in locus coeruleus. | 2 |
| 36527113 | 2022 | SPTBN1 abrogates renal clear cell carcinoma progression via glycolysis reprogramming in a GPT2-dependent manner. | 4 |
| 33368291 | 2021 | Abrogating GPT2 in triple-negative breast cancer inhibits tumor growth and promotes autophagy. | 11 |
| 33812407 | 2021 | [The Influence of Glutamic Pyruvate Transaminase 2 to Biological Characteristics of Acute Myeloid Leukemia Cell HL-60]. | 0 |
| 33368291 | 2021 | Abrogating GPT2 in triple-negative breast cancer inhibits tumor growth and promotes autophagy. | 11 |
| 33812407 | 2021 | [The Influence of Glutamic Pyruvate Transaminase 2 to Biological Characteristics of Acute Myeloid Leukemia Cell HL-60]. | 0 |
| 31978613 | 2020 | A novel missense variant in GPT2 causes non-syndromic autosomal recessive intellectual disability in a consanguineous Iranian family. | 2 |
Citation
Dessen P
GPT2 (glutamic--pyruvic transaminase 2)
Atlas Genet Cytogenet Oncol Haematol. 2021-06-01
Online version: http://atlasgeneticsoncology.org/gene/58388/submit-meetings/gene-explorer/
