Identity
HGNC
LOCATION
16q22.1
LOCUSID
ALIAS
AARS,CMT2N,DEE29,EIEE29
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 16
MIM: 601065
HGNC: 20
Ensembl: ENSG00000090861
Variants:
dbSNP: 16
ClinVar: 16
TCGA: ENSG00000090861
COSMIC: AARS1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000090861 | ENST00000261772 | P49588 |
| ENSG00000090861 | ENST00000565361 | H3BPK7 |
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38512451 | 2024 | The alanyl-tRNA synthetase AARS1 moonlights as a lactyltransferase to promote YAP signaling in gastric cancer. | 0 |
| 38653238 | 2024 | Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis. | 2 |
| 38512451 | 2024 | The alanyl-tRNA synthetase AARS1 moonlights as a lactyltransferase to promote YAP signaling in gastric cancer. | 0 |
| 38653238 | 2024 | Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis. | 2 |
| 37010095 | 2023 | A humanized yeast model reveals dominant-negative properties of neuropathy-associated alanyl-tRNA synthetase mutations. | 1 |
| 37010095 | 2023 | A humanized yeast model reveals dominant-negative properties of neuropathy-associated alanyl-tRNA synthetase mutations. | 1 |
| 35971119 | 2022 | Clinical characteristics and proteome modifications in two Charcot-Marie-Tooth families with the AARS1 Arg326Trp mutation. | 1 |
| 35971119 | 2022 | Clinical characteristics and proteome modifications in two Charcot-Marie-Tooth families with the AARS1 Arg326Trp mutation. | 1 |
| 33753480 | 2021 | CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS. | 15 |
| 33909043 | 2021 | Protein instability associated with AARS1 and MARS1 mutations causes trichothiodystrophy. | 15 |
| 33753480 | 2021 | CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS. | 15 |
| 33909043 | 2021 | Protein instability associated with AARS1 and MARS1 mutations causes trichothiodystrophy. | 15 |
| 32314272 | 2020 | Alanyl-tRNA synthetase 1 (AARS1) gene mutation in a family with intermediate Charcot-Marie-Tooth neuropathy. | 12 |
| 32314272 | 2020 | Alanyl-tRNA synthetase 1 (AARS1) gene mutation in a family with intermediate Charcot-Marie-Tooth neuropathy. | 12 |
| 30952159 | 2019 | The G3-U70-independent tRNA recognition by human mitochondrial alanyl-tRNA synthetase. | 20 |
Citation
Dessen P
AARS1 (alanyl-tRNA synthetase 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/60019/aars1-(alanyl-trna-synthetase-1)
