Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 33
MIM: 609576
HGNC: 88
Ensembl: ENSG00000115361
Variants:
dbSNP: 33
ClinVar: 33
TCGA: ENSG00000115361
COSMIC: ACADL
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115361 | ENST00000233710 | P28330 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36929466 | 2023 | ACADL suppresses PD-L1 expression to prevent cancer immune evasion by targeting Hippo/YAP signaling in lung adenocarcinoma. | 6 |
| 37151879 | 2023 | Bulk and single-cell transcriptome profiling reveal extracellular matrix mechanical regulation of lipid metabolism reprograming through YAP/TEAD4/ACADL axis in hepatocellular carcinoma. | 9 |
| 36929466 | 2023 | ACADL suppresses PD-L1 expression to prevent cancer immune evasion by targeting Hippo/YAP signaling in lung adenocarcinoma. | 6 |
| 37151879 | 2023 | Bulk and single-cell transcriptome profiling reveal extracellular matrix mechanical regulation of lipid metabolism reprograming through YAP/TEAD4/ACADL axis in hepatocellular carcinoma. | 9 |
| 33610471 | 2021 | Clinical outcomes in a series of 18 patients with long chain fatty acids oxidation disorders treated with triheptanoin for a median duration of 22 months. | 3 |
| 33610471 | 2021 | Clinical outcomes in a series of 18 patients with long chain fatty acids oxidation disorders treated with triheptanoin for a median duration of 22 months. | 3 |
| 32389575 | 2020 | The common K333Q polymorphism in long-chain acyl-CoA dehydrogenase (LCAD) reduces enzyme stability and function. | 6 |
| 32389575 | 2020 | The common K333Q polymorphism in long-chain acyl-CoA dehydrogenase (LCAD) reduces enzyme stability and function. | 6 |
| 31234015 | 2019 | The fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase can be a source of mitochondrial hydrogen peroxide. | 24 |
| 31234015 | 2019 | The fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase can be a source of mitochondrial hydrogen peroxide. | 24 |
| 24591516 | 2014 | Long-chain acyl-CoA dehydrogenase deficiency as a cause of pulmonary surfactant dysfunction. | 30 |
| 24591516 | 2014 | Long-chain acyl-CoA dehydrogenase deficiency as a cause of pulmonary surfactant dysfunction. | 30 |
| 24121500 | 2013 | Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site. | 87 |
| 24121500 | 2013 | Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site. | 87 |
| 20037589 | 2010 | A genome-wide perspective of genetic variation in human metabolism. | 323 |
Citation
Dessen P
ACADL (acyl-CoA dehydrogenase long chain)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/60072/gene-explorer/
