ACP6 (acid phosphatase 6, lysophosphatidic)

2014-11-01  

Identity

HGNC
ACP6
LOCATION
1q21.2
LOCUSID
51205
ALIAS
ACPL1,LPAP,PACPL1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51205
MIM: 611471
HGNC: 29609
Ensembl: ENSG00000162836

Variants:

dbSNP: 51205
ClinVar: 51205
TCGA: ENSG00000162836
COSMIC: ACP6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162836ENST00000392988A0A0A0MS36
ENSG00000162836ENST00000487562Q9NPH0
ENSG00000162836ENST00000487562X5D319
ENSG00000162836ENST00000493129A0A087WW36
ENSG00000162836ENST00000583509Q9NPH0
ENSG00000162836ENST00000609196V9GZ71
ENSG00000162836ENST00000611629A0A087WYU6
ENSG00000162836ENST00000620634A0A087WWB7

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Synthesis of PAREACTOMER-HSA-1483166

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
364569312022The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma.3
364569312022The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma.3
309146572019Mutant p53 regulates LPA signaling through lysophosphatidic acid phosphatase type 6.13
309146572019Mutant p53 regulates LPA signaling through lysophosphatidic acid phosphatase type 6.13
238076342013Crystal structures and biochemical studies of human lysophosphatidic acid phosphatase type 6.4
238076342013Crystal structures and biochemical studies of human lysophosphatidic acid phosphatase type 6.4
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
152800422004Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma.26
152800422004Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma.26
120108802002Novel human and mouse genes encoding an acid phosphatase family member and its downregulation in W/W(V) mouse jejunum.2
120108802002Novel human and mouse genes encoding an acid phosphatase family member and its downregulation in W/W(V) mouse jejunum.2

Citation

Dessen P

ACP6 (acid phosphatase 6, lysophosphatidic)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60096/acp6-(acid-phosphatase-6-lysophosphatidic)