ADAP2 (ArfGAP with dual PH domains 2)

2014-11-01  

Identity

HGNC
ADAP2
LOCATION
17q11.2
LOCUSID
55803
ALIAS
CENTA2,HSA272195,cent-b
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55803
MIM: 608635
HGNC: 16487
Ensembl: ENSG00000184060

Variants:

dbSNP: 55803
ClinVar: 55803
TCGA: ENSG00000184060
COSMIC: ADAP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184060ENST00000330889Q9NPF8
ENSG00000184060ENST00000580525Q2V6Q1
ENSG00000184060ENST00000580526J3KT70
ENSG00000184060ENST00000581285J3QRD3
ENSG00000184060ENST00000581548K7ENT1
ENSG00000184060ENST00000584828J3QLP8
ENSG00000184060ENST00000584989J3KST1
ENSG00000184060ENST00000585130J3QRA6

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
361272532023Elevated Expression of ADAP2 is Associated With Aggressive Behavior of Human Clear-Cell Renal Cell Carcinoma and Poor Patient Survival.0
361272532023Elevated Expression of ADAP2 is Associated With Aggressive Behavior of Human Clear-Cell Renal Cell Carcinoma and Poor Patient Survival.0
279567052017ArfGAP Domain-Containing Protein 2 (ADAP2) Integrates Upstream and Downstream Modules of RIG-I Signaling and Facilitates Type I Interferon Production.9
279567052017ArfGAP Domain-Containing Protein 2 (ADAP2) Integrates Upstream and Downstream Modules of RIG-I Signaling and Facilitates Type I Interferon Production.9
263726452015ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry.25
263726452015ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry.25
232852092012Centaurin-α₂ interacts with β-tubulin and stabilizes microtubules.8
232852092012Centaurin-α₂ interacts with β-tubulin and stabilizes microtubules.8
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
205466122010The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.28
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
205466122010The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.28
192660772009Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.62
192917642009RNF135 mutations are not present in patients with Sotos syndrome-like features.4
192660772009Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.62

Citation

Dessen P

ADAP2 (ArfGAP with dual PH domains 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60148/adap2-(arfgap-with-dual-ph-domains-2)