AEBP2 (AE binding protein 2)

2014-11-01  

Identity

HGNC
LOCATION
12p12.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 121536
MIM: 617934
HGNC: 24051
Ensembl: ENSG00000139154

Variants:

dbSNP: 121536
ClinVar: 121536
TCGA: ENSG00000139154
COSMIC: AEBP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139154ENST00000266508Q6ZN18
ENSG00000139154ENST00000360995Q6ZN18
ENSG00000139154ENST00000398731H7BYT4
ENSG00000139154ENST00000398864Q6ZN18
ENSG00000139154ENST00000512223H0YH08
ENSG00000139154ENST00000538425F5GZR7
ENSG00000139154ENST00000541908G5EA50

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Epigenetic regulation of gene expressionREACTOMER-HSA-212165
PRC2 methylates histones and DNAREACTOMER-HSA-212300
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
PKMTs methylate histone lysinesREACTOMER-HSA-3214841

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
334791232021JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications.92
334791232021JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications.92
318647062020β-TRCP-mediated AEBP2 ubiquitination and destruction controls cisplatin resistance in ovarian cancer.12
318647062020β-TRCP-mediated AEBP2 ubiquitination and destruction controls cisplatin resistance in ovarian cancer.12
291345162018Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4.8
291345162018Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4.8
259159012015Retrotransposon-derived promoter of Mammalian Aebp2.0
259159012015Retrotransposon-derived promoter of Mammalian Aebp2.0
231102522012Molecular architecture of human polycomb repressive complex 2.123
231102522012Molecular architecture of human polycomb repressive complex 2.123

Citation

Dessen P

AEBP2 (AE binding protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60178/aebp2-(ae-binding-protein-2)