Identity
HGNC
LOCATION
2q37.2
LOCUSID
ALIAS
AGAP-1,CENTG2,GGAP1,cnt-g2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 116987
MIM: 608651
HGNC: 16922
Ensembl: ENSG00000157985
Variants:
dbSNP: 116987
ClinVar: 116987
TCGA: ENSG00000157985
COSMIC: AGAP1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Endocytosis | KEGG | ko04144 |
| Endocytosis | KEGG | hsa04144 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33618745 | 2021 | CircAGAP1 promotes tumor progression by sponging miR-15-5p in clear cell renal cell carcinoma. | 17 |
| 33830075 | 2021 | Crystal structure of the GTP-binding protein-like domain of AGAP1. | 3 |
| 33618745 | 2021 | CircAGAP1 promotes tumor progression by sponging miR-15-5p in clear cell renal cell carcinoma. | 17 |
| 33830075 | 2021 | Crystal structure of the GTP-binding protein-like domain of AGAP1. | 3 |
| 31785816 | 2020 | AGAP1 regulates subcellular localization of FilGAP and control cancer cell invasion. | 7 |
| 31785816 | 2020 | AGAP1 regulates subcellular localization of FilGAP and control cancer cell invasion. | 7 |
| 28430047 | 2019 | Arf GAPs and molecular motors. | 6 |
| 28430047 | 2019 | Arf GAPs and molecular motors. | 6 |
| 27531749 | 2016 | Direct Functional Interaction of the Kinesin-13 Family Member Kinesin-like Protein 2A (Kif2A) and Arf GAP with GTP-binding Protein-like, Ankyrin Repeats and PH Domains1 (AGAP1). | 1 |
| 27531749 | 2016 | Direct Functional Interaction of the Kinesin-13 Family Member Kinesin-like Protein 2A (Kif2A) and Arf GAP with GTP-binding Protein-like, Ankyrin Repeats and PH Domains1 (AGAP1). | 1 |
| 22453919 | 2012 | GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity. | 10 |
| 22453919 | 2012 | GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity. | 10 |
| 18003747 | 2008 | Substrate specificities and activities of AZAP family Arf GAPs in vivo. | 13 |
| 18003747 | 2008 | Substrate specificities and activities of AZAP family Arf GAPs in vivo. | 13 |
| 15892143 | 2005 | Evaluation of the chromosome 2q37.3 gene CENTG2 as an autism susceptibility gene. | 25 |
Citation
Dessen P
AGAP1 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/60185/agap1-(arfgap-with-gtpase-domain-ankyrin-repeat-and-ph-domain-1)
