AGTPBP1 (ATP/GTP binding carboxypeptidase 1)

2014-11-01  

Identity

HGNC
LOCATION
9q21.33
LOCUSID
ALIAS
CCP1,CONDCA,NNA1
FUSION GENES

Other Information

Locus ID:

NCBI: 23287
MIM: 606830
HGNC: 17258
Ensembl: ENSG00000135049

Variants:

dbSNP: 23287
ClinVar: 23287
TCGA: ENSG00000135049
COSMIC: AGTPBP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135049ENST00000337006J3KNS1
ENSG00000135049ENST00000357081Q9UPW5
ENSG00000135049ENST00000376083Q9UPW5
ENSG00000135049ENST00000376083A0A024R288
ENSG00000135049ENST00000628899Q9UPW5

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
379378092024Deleterious genetic changes in AGTPBP1 result in teratozoospermia with sperm head and flagella defects.4
379378092024Deleterious genetic changes in AGTPBP1 result in teratozoospermia with sperm head and flagella defects.4
346378982022The AGTPBP1 gene in neurobiology.4
346378982022The AGTPBP1 gene in neurobiology.4
339091732021A novel pathogenic variant in the 3' end of the AGTPBP1 gene gives rise to neurodegeneration without cerebellar atrophy: an expansion of the disease phenotype?4
339091732021A novel pathogenic variant in the 3' end of the AGTPBP1 gene gives rise to neurodegeneration without cerebellar atrophy: an expansion of the disease phenotype?4
309761132019Biallelic variants in AGTPBP1, involved in tubulin deglutamylation, are associated with cerebellar degeneration and motor neuropathy.12
309761132019Biallelic variants in AGTPBP1, involved in tubulin deglutamylation, are associated with cerebellar degeneration and motor neuropathy.12
304205572018Loss of tubulin deglutamylase CCP1 causes infantile-onset neurodegeneration.50
304205572018Loss of tubulin deglutamylase CCP1 causes infantile-onset neurodegeneration.50
253810602015C-terminomics screen for natural substrates of cytosolic carboxypeptidase 1 reveals processing of acidic protein C termini.10
253810602015C-terminomics screen for natural substrates of cytosolic carboxypeptidase 1 reveals processing of acidic protein C termini.10
232425542013Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry.57
232425542013Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry.57

Citation

Dessen P

AGTPBP1 (ATP/GTP binding carboxypeptidase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60209/agtpbp1-(atp-gtp-binding-carboxypeptidase-1)