AOC2 (amine oxidase copper containing 2)

2014-11-01  

Identity

HGNC
LOCATION
17q21.31
LOCUSID
ALIAS
DAO2,RAO,SSAO

Other Information

Locus ID:

NCBI: 314
MIM: 602268
HGNC: 549
Ensembl: ENSG00000131480

Variants:

dbSNP: 314
ClinVar: 314
TCGA: ENSG00000131480
COSMIC: AOC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131480ENST00000253799O75106
ENSG00000131480ENST00000452774O75106

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Glycine, serine and threonine metabolismKEGGko00260
Tyrosine metabolismKEGGko00350
Phenylalanine metabolismKEGGko00360
beta-Alanine metabolismKEGGko00410
Glycine, serine and threonine metabolismKEGGhsa00260
Tyrosine metabolismKEGGhsa00350
Phenylalanine metabolismKEGGhsa00360
beta-Alanine metabolismKEGGhsa00410
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase 1 - Functionalization of compoundsREACTOMER-HSA-211945

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
277665852016Anatomical distribution of primary amine oxidase activity in four adipose depots and plasma of severely obese women with or without a dysmetabolic profile.7
277665852016Anatomical distribution of primary amine oxidase activity in four adipose depots and plasma of severely obese women with or without a dysmetabolic profile.7
195880762009The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase.15
195880762009The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase.15

Citation

Dessen P

AOC2 (amine oxidase copper containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60392/submit-meetings/new-content/