AP5M1 (adaptor related protein complex 5 subunit mu 1)

2014-11-01  

Identity

HGNC
AP5M1
LOCATION
14q22.3
LOCUSID
55745
ALIAS
C14orf108,MUDENG,Mu5,MuD
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55745
MIM: 614368
HGNC: 20192
Ensembl: ENSG00000053770

Variants:

dbSNP: 55745
ClinVar: 55745
TCGA: ENSG00000053770
COSMIC: AP5M1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000053770ENST00000261558Q9H0R1
ENSG00000053770ENST00000261558A0A024R654
ENSG00000053770ENST00000431972E7EQ45
ENSG00000053770ENST00000554863S4R311
ENSG00000053770ENST00000555448G3V3L4
ENSG00000053770ENST00000556377H0YIY0
ENSG00000053770ENST00000556995G3V573

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
183955202008A novel protein, MUDENG, induces cell death in cytotoxic T cells.5
236650152013MUDENG is cleaved by caspase-3 during TRAIL-induced cell death.3
314270812019BAX is an essential key mediator of AP5M1-induced apoptosis in cervical carcinoma cells.1

Citation

Dessen P

AP5M1 (adaptor related protein complex 5 subunit mu 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60413/ap5m1-(adaptor-related-protein-complex-5-subunit-mu-1)