Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 116519
MIM: 606368
HGNC: 17288
Ensembl: ENSG00000110243
Variants:
dbSNP: 116519
ClinVar: 116519
TCGA: ENSG00000110243
COSMIC: APOA5
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164742099 | MTTP | Gene | Pathway | associated | |||
| PA444528 | Hyperlipidemias | Disease | ClinicalAnnotation | associated | PD | 19530961 | |
| PA446120 | Hypertriglyceridemia | Disease | ClinicalAnnotation | associated | PD | 17431185, 19056598, 19057464 | |
| PA448500 | atorvastatin | Chemical | ClinicalAnnotation | associated | PD | 19530961 | |
| PA449594 | fenofibrate | Chemical | ClinicalAnnotation | associated | PD | 17431185, 19056598, 19057464 | |
| PA450272 | lovastatin | Chemical | ClinicalAnnotation | associated | PD | 19530961 | |
| PA451363 | simvastatin | Chemical | ClinicalAnnotation | associated | PD | 19530961 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38117614 | 2024 | Genetic variation in apolipoprotein A-V in hypertriglyceridemia. | 0 |
| 38331899 | 2024 | The pathogenic mutations of APOA5 in Chinese patients with hyperlipidemic acute pancreatitis. | 0 |
| 38117614 | 2024 | Genetic variation in apolipoprotein A-V in hypertriglyceridemia. | 0 |
| 38331899 | 2024 | The pathogenic mutations of APOA5 in Chinese patients with hyperlipidemic acute pancreatitis. | 0 |
| 36855913 | 2023 | Association of S19W polymorphism in APOA5 gene and serum lipid levels in patients with type 2 diabetic nephropathy. | 0 |
| 36921196 | 2023 | Investigation of associations between apolipoprotein A5 and C3 gene polymorphisms with plasma triglyceride and lipid levels. | 0 |
| 37586912 | 2023 | Variability of longitudinal triglyceride phenotype in patients heterozygous for pathogenic APOA5 variants. | 1 |
| 37768328 | 2023 | Association of Apolipoprotein A5 Gene Variants with Hyperlipidemic Acute Pancreatitis in Southeastern China. | 0 |
| 36855913 | 2023 | Association of S19W polymorphism in APOA5 gene and serum lipid levels in patients with type 2 diabetic nephropathy. | 0 |
| 36921196 | 2023 | Investigation of associations between apolipoprotein A5 and C3 gene polymorphisms with plasma triglyceride and lipid levels. | 0 |
| 37586912 | 2023 | Variability of longitudinal triglyceride phenotype in patients heterozygous for pathogenic APOA5 variants. | 1 |
| 37768328 | 2023 | Association of Apolipoprotein A5 Gene Variants with Hyperlipidemic Acute Pancreatitis in Southeastern China. | 0 |
| 19592705 | 2022 | PEA-15 engages in allosteric interactions using a common scaffold in a phosphorylation-dependent manner. | 24 |
| 35278410 | 2022 | Apolipoprotein A-V is a potential target for treating coronary artery disease: evidence from genetic and metabolomic analyses. | 1 |
| 35461093 | 2022 | Changes in adiposity modulate the APOA5 genetic effect on blood lipids: A longitudinal cohort study. | 1 |
Citation
Dessen P
APOA5 (apolipoprotein A5)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/60424/apoa5-(apolipoprotein-a5)
