APOBEC3D (apolipoprotein B mRNA editing enzyme catalytic subunit 3D)

2014-11-01  

Identity

HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
A3D,A3DE,APOBEC3DE,APOBEC3E,ARP6

Other Information

Locus ID:

NCBI: 140564
MIM: 609900
HGNC: 17354
Ensembl: ENSG00000243811

Variants:

dbSNP: 140564
ClinVar: 140564
TCGA: ENSG00000243811
COSMIC: APOBEC3D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000243811ENST00000216099Q96AK3
ENSG00000243811ENST00000216099B2CML4
ENSG00000243811ENST00000427494Q6ICH2
ENSG00000243811ENST00000622217A0A087WX48

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
325335152020Alternative splicing of APOBEC3D generates functional diversity and its role as a DNA mutator.3
325335152020Alternative splicing of APOBEC3D generates functional diversity and its role as a DNA mutator.3
272890672016APOBEC3DE Antagonizes Hepatitis B Virus Restriction Factors APOBEC3F and APOBEC3G.10
274283322016APOBEC3DE Inhibits LINE-1 Retrotransposition by Interacting with ORF1p and Influencing LINE Reverse Transcriptase Activity.19
274397152016APOBEC3 proteins can copackage and comutate HIV-1 genomes.20
272890672016APOBEC3DE Antagonizes Hepatitis B Virus Restriction Factors APOBEC3F and APOBEC3G.10
274283322016APOBEC3DE Inhibits LINE-1 Retrotransposition by Interacting with ORF1p and Influencing LINE Reverse Transcriptase Activity.19
274397152016APOBEC3 proteins can copackage and comutate HIV-1 genomes.20
242278422014APOBEC3 deaminases induce hypermutation in human papillomavirus 16 DNA upon beta interferon stimulation.45
253301462014APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model.53
242278422014APOBEC3 deaminases induce hypermutation in human papillomavirus 16 DNA upon beta interferon stimulation.45
253301462014APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model.53
230974382013APOBEC3G restricts HIV-1 to a greater extent than APOBEC3F and APOBEC3DE in human primary CD4+ T cells and macrophages.78
237559662013Identification and antiviral activity of common polymorphisms in the APOBEC3 locus in human populations.28
230974382013APOBEC3G restricts HIV-1 to a greater extent than APOBEC3F and APOBEC3DE in human primary CD4+ T cells and macrophages.78

Citation

Dessen P

APOBEC3D (apolipoprotein B mRNA editing enzyme catalytic subunit 3D)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60427/apobec3d-(apolipoprotein-b-mrna-editing-enzyme-catalytic-subunit-3d)