ARHGAP11B (Rho GTPase activating protein 11B)

2014-11-01  

Identity

HGNC
LOCATION
15q13.2
LOCUSID
ALIAS
B-T,FAM7B1,GAP (1-8)

Other Information

Locus ID:

NCBI: 89839
MIM: 616310
HGNC: 15782
Ensembl: ENSG00000284906

Variants:

dbSNP: 89839
ClinVar: 89839
TCGA: ENSG00000284906
COSMIC: ARHGAP11B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000284906ENST00000563110Q3KRB8
ENSG00000284906ENST00000622744Q3KRB8

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

References

Pubmed IDYearTitleCitations
257215032015Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion.142
279575442016A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification.14
304847712018Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex.6

Citation

Dessen P

ARHGAP11B (Rho GTPase activating protein 11B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60459/arhgap11b-(rho-gtpase-activating-protein-11b)