Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 89839
MIM: 616310
HGNC: 15782
Ensembl: ENSG00000284906
Variants:
dbSNP: 89839
ClinVar: 89839
TCGA: ENSG00000284906
COSMIC: ARHGAP11B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000284906 | ENST00000563110 | Q3KRB8 |
| ENSG00000284906 | ENST00000622744 | Q3KRB8 |
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Rho GTPases | REACTOME | R-HSA-194315 |
| Rho GTPase cycle | REACTOME | R-HSA-194840 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38046902 | 2023 | Protooncogenic Role of ARHGAP11A and ARHGAP11B in Invasive Ductal Carcinoma: Two Promising Breast Cancer Biomarkers. | 1 |
| 38046902 | 2023 | Protooncogenic Role of ARHGAP11A and ARHGAP11B in Invasive Ductal Carcinoma: Two Promising Breast Cancer Biomarkers. | 1 |
| 36098218 | 2022 | Human-specific ARHGAP11B ensures human-like basal progenitor levels in hominid cerebral organoids. | 7 |
| 36098218 | 2022 | Human-specific ARHGAP11B ensures human-like basal progenitor levels in hominid cerebral organoids. | 7 |
| 33938018 | 2021 | Expression of human-specific ARHGAP11B in mice leads to neocortex expansion and increased memory flexibility. | 19 |
| 33938018 | 2021 | Expression of human-specific ARHGAP11B in mice leads to neocortex expansion and increased memory flexibility. | 19 |
| 31883789 | 2020 | Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis. | 57 |
| 32554627 | 2020 | Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset. | 72 |
| 31883789 | 2020 | Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis. | 57 |
| 32554627 | 2020 | Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset. | 72 |
| 30484771 | 2018 | Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex. | 44 |
| 30484771 | 2018 | Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex. | 44 |
| 27957544 | 2016 | A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification. | 37 |
| 27957544 | 2016 | A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification. | 37 |
| 25721503 | 2015 | Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion. | 272 |
Citation
Dessen P
ARHGAP11B (Rho GTPase activating protein 11B)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/60459/arhgap11b-(rho-gtpase-activating-protein-11b)
