Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 550
MIM: 602434
HGNC: 891
Ensembl: ENSG00000115307
Variants:
dbSNP: 550
ClinVar: 550
TCGA: ENSG00000115307
COSMIC: AUP1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115307 | ENST00000377526 | Q9Y679 |
| ENSG00000115307 | ENST00000425118 | Q9Y679 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38474353 | 2024 | AUP1 Regulates the Endoplasmic Reticulum-Associated Degradation and Polyubiquitination of NKCC2. | 1 |
| 38474353 | 2024 | AUP1 Regulates the Endoplasmic Reticulum-Associated Degradation and Polyubiquitination of NKCC2. | 1 |
| 35633317 | 2022 | AUP1 regulates lipid metabolism and induces lipid accumulation to accelerate the progression of renal clear cell carcinoma. | 10 |
| 35633317 | 2022 | AUP1 regulates lipid metabolism and induces lipid accumulation to accelerate the progression of renal clear cell carcinoma. | 10 |
| 34879065 | 2021 | A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation. | 5 |
| 34879065 | 2021 | A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation. | 5 |
| 28183703 | 2017 | AUP1 (Ancient Ubiquitous Protein 1) Is a Key Determinant of Hepatic Very-Low-Density Lipoprotein Assembly and Secretion. | 8 |
| 28183703 | 2017 | AUP1 (Ancient Ubiquitous Protein 1) Is a Key Determinant of Hepatic Very-Low-Density Lipoprotein Assembly and Secretion. | 8 |
| 23197321 | 2013 | Monotopic topology is required for lipid droplet targeting of ancient ubiquitous protein 1. | 25 |
| 23223569 | 2013 | Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes. | 50 |
| 24039768 | 2013 | Monoubiquitination of ancient ubiquitous protein 1 promotes lipid droplet clustering. | 13 |
| 23197321 | 2013 | Monotopic topology is required for lipid droplet targeting of ancient ubiquitous protein 1. | 25 |
| 23223569 | 2013 | Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes. | 50 |
| 24039768 | 2013 | Monoubiquitination of ancient ubiquitous protein 1 promotes lipid droplet clustering. | 13 |
| 21127063 | 2011 | Ancient ubiquitous protein 1 (AUP1) localizes to lipid droplets and binds the E2 ubiquitin conjugase G2 (Ube2g2) via its G2 binding region. | 60 |
Citation
Dessen P
AUP1 (AUP1 lipid droplet regulating VLDL assembly factor)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/60665/aup1-(aup1-lipid-droplet-regulating-vldl-assembly-factor)
