Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 266675
MIM: 607336
HGNC: 17106
Ensembl: ENSG00000142959
Variants:
dbSNP: 266675
ClinVar: 266675
TCGA: ENSG00000142959
COSMIC: BEST4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000142959 | ENST00000372207 | Q8NFU0 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Transmembrane transport of small molecules | REACTOME | R-HSA-382551 |
| Ion channel transport | REACTOME | R-HSA-983712 |
| Stimuli-sensing channels | REACTOME | R-HSA-2672351 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35058597 | 2022 | Oncogenic potential of BEST4 in colorectal cancer via activation of PI3K/Akt signaling. | 5 |
| 35058597 | 2022 | Oncogenic potential of BEST4 in colorectal cancer via activation of PI3K/Akt signaling. | 5 |
| 24223998 | 2013 | Lineage-specific expression of bestrophin-2 and bestrophin-4 in human intestinal epithelial cells. | 21 |
| 24223998 | 2013 | Lineage-specific expression of bestrophin-2 and bestrophin-4 in human intestinal epithelial cells. | 21 |
| 19237432 | 2009 | Bestrophin expression and function in the human pancreatic duct cell line, CFPAC-1. | 8 |
| 19237432 | 2009 | Bestrophin expression and function in the human pancreatic duct cell line, CFPAC-1. | 8 |
| 16702355 | 2006 | Ca2+-activated Cl- current from human bestrophin-4 in excised membrane patches. | 24 |
| 16702355 | 2006 | Ca2+-activated Cl- current from human bestrophin-4 in excised membrane patches. | 24 |
| 12032738 | 2002 | Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family. | 29 |
| 12032738 | 2002 | Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family. | 29 |
Citation
Dessen P
BEST4 (bestrophin 4)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/60742/best4-(bestrophin-4)
