BHLHE22 (basic helix-loop-helix family member e22)

2014-11-01  

Identity

HGNC
BHLHE22
LOCATION
8q12.3
LOCUSID
27319
ALIAS
BHLHB5,Beta3,Beta3a,CAGL85,TNRC20

Other Information

Locus ID:

NCBI: 27319
MIM: 613483
HGNC: 11963
Ensembl: ENSG00000180828

Variants:

dbSNP: 27319
ClinVar: 27319
TCGA: ENSG00000180828
COSMIC: BHLHE22

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000180828ENST00000321870Q8NFJ8

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
369410152023BHLHE22 drives the immunosuppressive bone tumor microenvironment and associated bone metastasis in prostate cancer.2
369410152023BHLHE22 drives the immunosuppressive bone tumor microenvironment and associated bone metastasis in prostate cancer.2
346645402022Rare variant association study of veteran twin whole-genomes links severe depression with a nonsynonymous change in the neuronal gene BHLHE22.0
358061622022BHLHE22 Expression Is Associated with a Proinflammatory Immune Microenvironment and Confers a Favorable Prognosis in Endometrial Cancer.2
346645402022Rare variant association study of veteran twin whole-genomes links severe depression with a nonsynonymous change in the neuronal gene BHLHE22.0
358061622022BHLHE22 Expression Is Associated with a Proinflammatory Immune Microenvironment and Confers a Favorable Prognosis in Endometrial Cancer.2
122132012002Functional and structural characterization of the human gene BHLHB5, encoding a basic helix-loop-helix transcription factor.23
122132012002Functional and structural characterization of the human gene BHLHB5, encoding a basic helix-loop-helix transcription factor.23

Citation

Dessen P

BHLHE22 (basic helix-loop-helix family member e22)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60751/bhlhe22-(basic-helix-loop-helix-family-member-e22)