HROB (homologous recombination factor with OB-fold)

2014-11-01  

Identity

HGNC
LOCATION
17q21.31
LOCUSID
ALIAS
C17orf53,MCM8IP

Other Information

Locus ID:

NCBI: 78995
MIM: 618611
HGNC: 28460
Ensembl: ENSG00000125319

Variants:

dbSNP: 78995
ClinVar: 78995
TCGA: ENSG00000125319
COSMIC: HROB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125319ENST00000245382Q8N3J3
ENSG00000125319ENST00000319977Q8N3J3
ENSG00000125319ENST00000585683Q8N3J3

References

Pubmed IDYearTitleCitations
386780262024Mechanism of DNA unwinding by MCM8-9 in complex with HROB.1
386780262024Mechanism of DNA unwinding by MCM8-9 in complex with HROB.1
347072992022Meiotic genes in premature ovarian insufficiency: variants in HROB and REC8 as likely genetic causes.12
347072992022Meiotic genes in premature ovarian insufficiency: variants in HROB and REC8 as likely genetic causes.12
325280602020MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage.22
328538262020C17orf53 is identified as a novel gene involved in inter-strand crosslink repair.12
325280602020MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage.22
328538262020C17orf53 is identified as a novel gene involved in inter-strand crosslink repair.12
303706072019Why SNP rs227584 is associated with human BMD and fracture risk? A molecular and cellular study in bone cells.3
314670872019Control of homologous recombination by the HROB-MCM8-MCM9 pathway.44
303706072019Why SNP rs227584 is associated with human BMD and fracture risk? A molecular and cellular study in bone cells.3
314670872019Control of homologous recombination by the HROB-MCM8-MCM9 pathway.44
190792622009New sequence variants associated with bone mineral density.141
190792622009New sequence variants associated with bone mineral density.141

Citation

Dessen P

HROB (homologous recombination factor with OB-fold)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60993/hrob-(homologous-recombination-factor-with-ob-fold)