Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 716
MIM: 120580
HGNC: 1247
Ensembl: ENSG00000182326
Variants:
dbSNP: 716
ClinVar: 716
TCGA: ENSG00000182326
COSMIC: C1S
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38218080 | 2024 | Cytoprotective effects of C1s enzyme in macrophages in atherosclerosis mediated through the LRP5 and Wnt/β-catenin pathway. | 0 |
| 38218080 | 2024 | Cytoprotective effects of C1s enzyme in macrophages in atherosclerosis mediated through the LRP5 and Wnt/β-catenin pathway. | 0 |
| 36960056 | 2023 | Degradation of collagen I by activated C1s in periodontal Ehlers-Danlos Syndrome. | 2 |
| 37209807 | 2023 | A homozygous loss-of-function C1S mutation is associated with Kikuchi-Fujimoto disease. | 0 |
| 36960056 | 2023 | Degradation of collagen I by activated C1s in periodontal Ehlers-Danlos Syndrome. | 2 |
| 37209807 | 2023 | A homozygous loss-of-function C1S mutation is associated with Kikuchi-Fujimoto disease. | 0 |
| 33804666 | 2021 | The Impact of Complement Genes on the Risk of Late-Onset Alzheimer's Disease. | 11 |
| 34155115 | 2021 | C1q binding to surface-bound IgG is stabilized by C1r(2)s(2) proteases. | 21 |
| 33804666 | 2021 | The Impact of Complement Genes on the Risk of Late-Onset Alzheimer's Disease. | 11 |
| 34155115 | 2021 | C1q binding to surface-bound IgG is stabilized by C1r(2)s(2) proteases. | 21 |
| 31921203 | 2019 | Two Different Missense C1S Mutations, Associated to Periodontal Ehlers-Danlos Syndrome, Lead to Identical Molecular Outcomes. | 6 |
| 31921203 | 2019 | Two Different Missense C1S Mutations, Associated to Periodontal Ehlers-Danlos Syndrome, Lead to Identical Molecular Outcomes. | 6 |
| 28104818 | 2017 | Structure and activation of C1, the complex initiating the classical pathway of the complement cascade. | 58 |
| 28104818 | 2017 | Structure and activation of C1, the complex initiating the classical pathway of the complement cascade. | 58 |
| 27745832 | 2016 | Periodontal Ehlers-Danlos Syndrome Is Caused by Mutations in C1R and C1S, which Encode Subcomponents C1r and C1s of Complement. | 38 |
Citation
Dessen P
C1S (complement C1s)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/61106/c1s-(complement-c1s)
